Literature DB >> 27239467

Polarizable Material from a Conjunctival Biopsy in a Patient with Sarcoidosis.

Omair B Ali1, Ryan Deroque1, R Grant Morshedi1, Harry Brown2.   

Abstract

PURPOSE: Conjunctival biopsies may contain polarizable material in patients with sarcoidosis despite no history of prior trauma or eye surgeries. PROCEDURES: A 39-year-old male with uveitic glaucoma presented with decreased vision and throbbing pain in his right eye. His intraocular pressure was elevated, and his vision was reduced to hand motion. Due to persistently elevated intraocular pressure refractory to medical treatment, the patient underwent a glaucoma drainage device procedure. During the procedure, a yellow, nodular conjunctival growth was noted and biopsied.
RESULTS: Histopathological examination revealed multiple nonnecrotizing granulomata, some of which contained polarizable material.
CONCLUSIONS: Biopsies of patients with sarcoidosis may contain polarizable material without evidence of foreign body inoculation.

Entities:  

Keywords:  Conjunctiva; Conjunctival biopsy; Foreign body; Polarizable material; Sarcoidosis; Uveitis glaucoma

Year:  2016        PMID: 27239467      PMCID: PMC4881259          DOI: 10.1159/000444260

Source DB:  PubMed          Journal:  Ocul Oncol Pathol        ISSN: 2296-4657


  8 in total

1.  Sarcoidosis in the national veteran population: association of ocular inflammation and mortality.

Authors:  Andrea D Birnbaum; Dustin D French; Mehdi Mirsaeidi; Sarah Wehrli
Journal:  Ophthalmology       Date:  2015-02-14       Impact factor: 12.079

2.  Foreign bodies in granulomatous cutaneous lesions of patients with systemic sarcoidosis.

Authors:  J Marcoval; J Mañá; A Moreno; I Gallego; Y Fortuño; J Peyrí
Journal:  Arch Dermatol       Date:  2001-04

Review 3.  Sarcoidosis: a Critical Review of History and Milestones.

Authors:  Paolo Spagnolo
Journal:  Clin Rev Allergy Immunol       Date:  2015-08       Impact factor: 8.667

4.  Value of measuring serum angiotensin I converting enzyme and serum lysozyme in the management of sarcoidosis.

Authors:  C W Turton; E Grundy; G Firth; D Mitchell; B G Rigden; M Turner-Warwick
Journal:  Thorax       Date:  1979-02       Impact factor: 9.139

Review 5.  Pathology of Sarcoidosis.

Authors:  Giulio Rossi; Alberto Cavazza; Thomas V Colby
Journal:  Clin Rev Allergy Immunol       Date:  2015-08       Impact factor: 8.667

6.  International criteria for the diagnosis of ocular sarcoidosis: results of the first International Workshop On Ocular Sarcoidosis (IWOS).

Authors:  Carl P Herbort; Narsing A Rao; Manabu Mochizuki
Journal:  Ocul Immunol Inflamm       Date:  2009 May-Jun       Impact factor: 3.070

7.  The clinical course of sarcoidosis: presentation, diagnosis, and treatment in a large white and black cohort in the United States.

Authors:  M A Judson; A D Boan; D T Lackland
Journal:  Sarcoidosis Vasc Diffuse Lung Dis       Date:  2012-10       Impact factor: 0.670

8.  Cutaneous sarcoidosis and foreign bodies.

Authors:  N M Walsh; J G Hanly; R Tremaine; S Murray
Journal:  Am J Dermatopathol       Date:  1993-06       Impact factor: 1.533

  8 in total

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