Literature DB >> 27239453

Uveal Melanoma Mimicking Advanced Coats' Disease in a Young Patient.

Naina Gupta1, William Terrell1, Lynn Schoenfield2, Claudia Kirsch3, Colleen M Cebulla1.   

Abstract

BACKGROUND/AIMS: To report a case and the unique histopathology of a necrotic uveal melanoma mimicking advanced Coats' disease in a young adult.
METHOD: A 26-year-old male presented with a blind, painful eye, total exudative retinal detachment, and bulbous aneurysms consistent with Coats' disease. No masses were visualized on ultrasound or CT scan, and the patient underwent enucleation of the eye.
RESULTS: Histopathology of the involved eye confirmed a necrotic uveal melanoma with persistent spindle cells forming a collar around residual tumor vessels.
CONCLUSION: Careful consideration is needed in approaching any patient with a blind, painful eye and opaque media, even in younger populations.

Entities:  

Keywords:  Coats’ disease; Necrotic choroidal melanoma; Uveal melanoma

Year:  2015        PMID: 27239453      PMCID: PMC4881292          DOI: 10.1159/000441526

Source DB:  PubMed          Journal:  Ocul Oncol Pathol        ISSN: 2296-4657


  11 in total

1.  Unsuspected intraocular malignant melanomas.

Authors:  T A MAKLEY; R W TEED
Journal:  AMA Arch Ophthalmol       Date:  1958-09

2.  Management of occult necrotic melanomas.

Authors:  Devron H Char; Tia B Cole; J Brooks Crawford
Journal:  JAMA Ophthalmol       Date:  2013-08       Impact factor: 7.389

3.  Dual-energy CT in the evaluation of intracerebral hemorrhage of unknown origin: differentiation between tumor bleeding and pure hemorrhage.

Authors:  S J Kim; H K Lim; H Y Lee; C G Choi; D H Lee; D C Suh; S M Kim; J K Kim; B Krauss
Journal:  AJNR Am J Neuroradiol       Date:  2012-01-12       Impact factor: 3.825

4.  Totally necrotic choroidal and ciliary body melanomas: associations with prognosis, episcleritis, and scleritis.

Authors:  A Moshari; E W Cheeseman; I W McLean
Journal:  Am J Ophthalmol       Date:  2001-02       Impact factor: 5.258

5.  Spontaneous Necrosis of Choroidal Melanoma.

Authors:  Shalini Thareja; Alia Rashid; Hans E Grossniklaus
Journal:  Ocul Oncol Pathol       Date:  2014-09-10

6.  Ocular inflammation and hemorrhage as initial manifestations of uveal malignant melanoma. Incidence and prognosis.

Authors:  D J Fraser; R L Font
Journal:  Arch Ophthalmol       Date:  1979-07

7.  Ocular melanoma.

Authors:  K A Tong; A G Osborn; N Mamalis; R P Harrie; N B Call
Journal:  AJNR Am J Neuroradiol       Date:  1993 Nov-Dec       Impact factor: 3.825

Review 8.  Advanced Coats' disease.

Authors:  B G Haik
Journal:  Trans Am Ophthalmol Soc       Date:  1991

9.  Uveal melanoma in teenagers and children. A report of 40 cases.

Authors:  C L Shields; J A Shields; J Milite; P De Potter; R Sabbagh; H Menduke
Journal:  Ophthalmology       Date:  1991-11       Impact factor: 12.079

10.  Inadvertent evisceration of eyes containing uveal melanoma.

Authors:  Ralph C Eagle; Hans E Grossniklaus; Nasreen Syed; R Nick Hogan; William C Lloyd; Robert Folberg
Journal:  Arch Ophthalmol       Date:  2009-02
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