L J Shi1, J F Liu1, Z Q Zhang1, Y Q Lu1, Y G Shu1, G L Chen1, Z H Xin1, J Y Xu1. 1. Lin-Jie Shi, Zi-Qiang Zhang, Guo-Lin Chen, Zhi-Hua Xin, Institute of Integrated TCM and Western Medicine, Hunan Medical University, Changsha 410008, Hunan Province, China.
Abstract
AIM: To investigate the pathophysiology of erythrocyte energy metabolic changes of patients with the traditional Chinese Medicine (TCM) liver-blood deficiency syndrome (LBDS). METHODS: Erythrocyte membrane ATPase activity and oxygen consumption rate (OCR) were determined in 66 patients with LBDS, including 35 patients with iron deficiency anemia and 31 patients with chronic aplastic anemia. Thirty healthy adults served as controls. RESULTS: ATPase activity and OCR were decreased in patients with LBDS. CONCLUSION: The decreased erythrocyte ATPase activity and OCR might cause the energy hypometabolism in LBDS patients.
AIM: To investigate the pathophysiology of erythrocyte energy metabolic changes of patients with the traditional Chinese Medicine (TCM) liver-blood deficiency syndrome (LBDS). METHODS: Erythrocyte membrane ATPase activity and oxygen consumption rate (OCR) were determined in 66 patients with LBDS, including 35 patients with iron deficiency anemia and 31 patients with chronic aplastic anemia. Thirty healthy adults served as controls. RESULTS:ATPase activity and OCR were decreased in patients with LBDS. CONCLUSION: The decreased erythrocyte ATPase activity and OCR might cause the energy hypometabolism in LBDS patients.