BACKGROUND: The aim of this study was to investigate the prognostic impact of acute-phase ventricular tachycardia and fibrillation (VT/VF) on ST-segment elevation myocardial infarction (STEMI) patients in the percutaneous coronary intervention (PCI) era. METHODS AND RESULTS: Using the database of the Osaka Acute Coronary Insufficiency Study (OACIS), we studied 4,283 consecutive patients with STEMI who were hospitalized within 12 h of STEMI onset and underwent emergency PCI. Acute-phase VT/VF, defined as ≥3 consecutive ventricular premature complexes and/or VF within the 1st week of hospitalization, occurred in 997 (23.3%) patients. In-hospital mortality risk was significantly higher in patients with acute-phase VT/VF than inthose without (14.6% vs. 4.3%, adjusted hazard ratio (HR) 1.83, P=0.0013). Among patients discharged alive, 5-year mortality rates were comparable between patients with and without acute-phase VT/VF. Subgroup analysis showed that acute-phase VT/VF was associated with increased 5-year mortality after discharge in high-risk patients (GRACE Risk Score ≥115; adjusted HR 1.60, P=0.043), but not in intermediate- or low-risk patients. CONCLUSIONS: Even in the PCI era, acute-phase VT/VF was associated with higher in-hospital deaths of STEMI patients. However, the 5-year prognostic impact of acute-phase VT/VF was limited to high-risk patients. (Circ J 2016; 80: 1539-1547).
BACKGROUND: The aim of this study was to investigate the prognostic impact of acute-phase ventricular tachycardia and fibrillation (VT/VF) on ST-segment elevation myocardial infarction (STEMI) patients in the percutaneous coronary intervention (PCI) era. METHODS AND RESULTS: Using the database of the Osaka Acute Coronary Insufficiency Study (OACIS), we studied 4,283 consecutive patients with STEMI who were hospitalized within 12 h of STEMI onset and underwent emergency PCI. Acute-phase VT/VF, defined as ≥3 consecutive ventricular premature complexes and/or VF within the 1st week of hospitalization, occurred in 997 (23.3%) patients. In-hospital mortality risk was significantly higher in patients with acute-phase VT/VF than inthose without (14.6% vs. 4.3%, adjusted hazard ratio (HR) 1.83, P=0.0013). Among patients discharged alive, 5-year mortality rates were comparable between patients with and without acute-phase VT/VF. Subgroup analysis showed that acute-phase VT/VF was associated with increased 5-year mortality after discharge in high-risk patients (GRACE Risk Score ≥115; adjusted HR 1.60, P=0.043), but not in intermediate- or low-risk patients. CONCLUSIONS: Even in the PCI era, acute-phase VT/VF was associated with higher in-hospital deaths of STEMI patients. However, the 5-year prognostic impact of acute-phase VT/VF was limited to high-risk patients. (Circ J 2016; 80: 1539-1547).
Authors: Kadriye Gayretli Yayla; Çağrı Yayla; Mehmet Akif Erdöl; Mustafa Karanfil; Hamza Sunman; Faruk Aydın Yılmaz; Nail Burak Özbeyaz; Ayşe Nur Özkaya İbiş; Murat Tulmaç Journal: Anatol J Cardiol Date: 2021-12 Impact factor: 1.596
Authors: Réka Skoda; Attila Nemes; György Bárczi; József Gajdácsi; Hajnalka Vágó; Zoltán Ruzsa; István F Édes; Liliána Szabó; Csilla Czimbalmos; Nóra Sydó; Elek Dinya; Béla Merkely; Dávid Becker Journal: Quant Imaging Med Surg Date: 2021-01
Authors: Laszlo B Szapary; Zsolt Szakacs; Nelli Farkas; Kristof Schonfeld; Dora Babocsay; Mate Gajer; Balint Kittka; Balazs Magyari; Peter Hegyi; Istvan Szokodi; Ivan G Horvath Journal: Front Cardiovasc Med Date: 2021-01-11
Authors: Mohammad Bakhriansyah; Patrick C Souverein; Olaf H Klungel; Anthonius de Boer; Marieke T Blom; Hanno L Tan Journal: Europace Date: 2019-01-01 Impact factor: 5.214