| Literature DB >> 27237948 |
M Leanne Ward1, Slavica Mijatovic-Rustempasic2, Sunando Roy3, Kunchala Rungsrisuriyachai4, Julie A Boom5, Leila C Sahni6, Carol J Baker7, Marcia A Rench8, Mary E Wikswo9, Daniel C Payne10, Umesh D Parashar11, Michael D Bowen12.
Abstract
Here we report the genome of a novel rotavirus A (RVA) strain detected in a stool sample collected during routine surveillance by the Centers for Disease Control and Prevention's New Vaccine Surveillance Network. The strain, RVA/human-wt/USA/2012741499/2012/G24P[14], has a genomic constellation of G24-P[14]-I2-R2-C2-M2-A3-N2-T9-E2-H3. The VP2, VP3, VP7 and NSP3 genes cluster phylogenetically with bovine strains. The other genes occupy mixed clades containing animal and human strains. Strain RVA/human-wt/USA/2012741499/2012/G24P[14] most likely is the product of interspecies transmission and reassortment events. This is the second report of the G24 genotype and the first report of the G24P[14] genotype combination in humans. Published by Elsevier B.V.Entities:
Keywords: Bovine; G24P[14]; Reassortment; Rotavirus
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Year: 2016 PMID: 27237948 PMCID: PMC5072358 DOI: 10.1016/j.meegid.2016.05.033
Source DB: PubMed Journal: Infect Genet Evol ISSN: 1567-1348 Impact factor: 3.342