Georgia Véras de Araujo1, Débora F B Leite2, José A Rizzo3, Emanuel S C Sarinho4. 1. Research Centre for Allergy and Clinical Immunology, Federal University of Pernambuco, Recife, PE, Brazil. Electronic address: georgiaveras@uol.com.br. 2. Department of Obstetrics and Gynecology, Federal University of Pernambuco, Recife, PE, Brazil. 3. Department of Pulmonology, Federal University of Pernambuco, Recife, PE, Brazil. 4. Department of Postgraduate Health Sciences, Federal University of Pernambuco, Recife, PE, Brazil.
Abstract
OBJECTIVE: The aim of this study was to identify a possible association between the assessment of clinical asthma control using the Asthma Control Test (ACT) and the Global Initiative for Asthma (GINA) classification and to perform comparisons with values of spirometry. STUDY DESIGN: Through this cross-sectional study, 103 pregnant women with asthma were assessed in the period from October 2010 to October 2013 in the asthma pregnancy clinic at the Clinical Hospital of the Federal University of Pernambuco. Questionnaires concerning the level of asthma control were administered using the Global Initiative for Asthma classification, the Asthma Control Test validated for asthmatic expectant mothers and spirometry; all three methods of assessing asthma control were performed during the same visit between the twenty-first and twenty-seventh weeks of pregnancy. RESULTS: There was a significant association between clinical asthma control assessment using the Asthma Control Test and the Global Initiative for Asthma classification (p<0.001). There were also significant associations between the results of the subjective instruments of asthma (the GINA classification and the ACT) and evidence of lung function by spirometry. CONCLUSIONS: This study shows that both the Global Initiative for Asthma classification and the Asthma Control Test can be used for asthmatic expectant mothers to assess the clinical control of asthma, especially at the end of the second trimester, which is assumed to be the period of worsening asthma exacerbations during pregnancy. We highlight the importance of the Asthma Control Test as a subjective instrument with easy application, easy interpretation and good reproducibility that does not require spirometry to assess the level of asthma control and can be used in the primary care of asthmatic expectant mothers.
OBJECTIVE: The aim of this study was to identify a possible association between the assessment of clinical asthma control using the Asthma Control Test (ACT) and the Global Initiative for Asthma (GINA) classification and to perform comparisons with values of spirometry. STUDY DESIGN: Through this cross-sectional study, 103 pregnant women with asthma were assessed in the period from October 2010 to October 2013 in the asthma pregnancy clinic at the Clinical Hospital of the Federal University of Pernambuco. Questionnaires concerning the level of asthma control were administered using the Global Initiative for Asthma classification, the Asthma Control Test validated for asthmatic expectant mothers and spirometry; all three methods of assessing asthma control were performed during the same visit between the twenty-first and twenty-seventh weeks of pregnancy. RESULTS: There was a significant association between clinical asthma control assessment using the Asthma Control Test and the Global Initiative for Asthma classification (p<0.001). There were also significant associations between the results of the subjective instruments of asthma (the GINA classification and the ACT) and evidence of lung function by spirometry. CONCLUSIONS: This study shows that both the Global Initiative for Asthma classification and the Asthma Control Test can be used for asthmatic expectant mothers to assess the clinical control of asthma, especially at the end of the second trimester, which is assumed to be the period of worsening asthma exacerbations during pregnancy. We highlight the importance of the Asthma Control Test as a subjective instrument with easy application, easy interpretation and good reproducibility that does not require spirometry to assess the level of asthma control and can be used in the primary care of asthmatic expectant mothers.
Authors: Hooman Mirzakhani; Vincent J Carey; Robert Zeiger; Leonard B Bacharier; George T O'Connor; Michael X Schatz; Nancy Laranjo; Scott T Weiss; Augusto A Litonjua Journal: Clin Exp Allergy Date: 2019-01-03 Impact factor: 5.018
Authors: Hooman Mirzakhani; Vincent J Carey; Thomas F McElrath; Nancy Laranjo; George O'Connor; Ronald E Iverson; Aviva Lee-Parritz; Robert C Strunk; Leonard B Bacharier; George A Macones; Robert S Zeiger; Michael Schatz; Bruce W Hollis; Augusto A Litonjua; Scott T Weiss Journal: J Allergy Clin Immunol Pract Date: 2017-09-08
Authors: Wanis H Ibrahim; Fatima Rasul; Mushtaq Ahmad; Abeer S Bajwa; Laith I Alamlih; Anam M El Arabi; Mujahed M Dauleh; Ibrahim Y Abubeker; Muhammed U Khan; Tayseer S Ibrahim; Azdin A Ibrahim Journal: Chron Respir Dis Date: 2018-04-05 Impact factor: 2.444
Authors: Wanis H Ibrahim; Fatima Rasul; Mushtaq Ahmad; Abeer S Bajwa; Laith I Alamlih; Anam M El Arabi; Dhabia Al-Mohannadi; Mohammed Y Siddiqui; Israa S Al-Sheikh; Azdin A Ibrahim Journal: Can Respir J Date: 2018-12-18 Impact factor: 2.409