Literature DB >> 27236545

Successful Aging and Frailty: Opposite Sides of the Same Coin?

Jean Woo1, Jason Leung2, Tiemei Zhang3.   

Abstract

OBJECTIVES: Operational definitions of successful aging place a strong emphasis on functional capacity, and strategies for successful aging include many factors common to frailty research. We explore the hypothesis that frailty and successful aging are two sides of the same coin and that walking speed may be an objective indicator of successful aging.
DESIGN: Observational study of two Chinese cohorts using one to define "fast walkers" and applying this criteria to another cohort to examine associated factors.
SETTING: Community survey in cities in China. PARTICIPANTS: A total of 1929 men and women aged 25 to 89 years of age in four cities in China and 4000 men and women 65 years old in Hong Kong SAR China. MEASUREMENTS: The top 25th percentile of walking speed for the whole cohort of 1929 men was determined, and the cutoff value was used to define "fast walkers." This value was applied to the Hong Kong Chinese population to examine factors associated with fast walking speed. These factors include age, gender, socioeconomic and lifestyle factors, medical history, quality of life, cognitive function, depressive symptoms, body mass index, body composition, and telomere length.
RESULTS: Fast walkers had better self-rated health, lower prevalence of stroke, hypertension, cataracts, osteoporosis, and impaired cognitive function. They were more likely to be current alcohol users, more physically active, consumed more vegetables, had better physical component of health-related quality of life, and received more education. They also had lower body mass index, percentage whole body fat as well as appendicular fat, and higher appendicular muscle mass index. In multivariate analysis, the significant contributing variables were age, gender, current alcohol use, physical activity level, vegetable intake, quality of life, and appendicular fat. The area under the curve value on receiver-operating characteristic analysis was 0.77 for these seven variables.
CONCLUSIONS: Frailty and successful aging may be considered two sides of the same entity, and fast walking speed may be used as an objective indicator of successful aging.
Copyright © 2016 AMDA – The Society for Post-Acute and Long-Term Care Medicine. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Frailty; appendicular fat; physical activity; quality of life; successful aging; walking speed

Mesh:

Year:  2016        PMID: 27236545     DOI: 10.1016/j.jamda.2016.04.015

Source DB:  PubMed          Journal:  J Am Med Dir Assoc        ISSN: 1525-8610            Impact factor:   4.669


  10 in total

Review 1.  Air Pollution and Successful Aging: Recent Evidence and New Perspectives.

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3.  Forging a Frailty-Ready Healthcare System to Meet Population Ageing.

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4.  Designing Fit for Purpose Health and Social Services for Ageing Populations.

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Journal:  Int J Environ Res Public Health       Date:  2017-04-25       Impact factor: 3.390

5.  Diet quality in relation to healthy ageing: the Israeli Longitudinal Study on Aging (ILSA)-a study protocol.

Authors:  Abigail Goshen; Uri Goldbourt; Tamar Shohat; Tal Shimony; Lital Keinan-Boker; Yariv Gerber
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8.  Frailty Risk in Older Adults Associated With Long-Term Exposure to Ambient PM2.5 in 6 Middle-Income Countries.

Authors:  Yanfei F Guo; Nawi Ng; Paul Kowal; Hualiang Lin; Ye Ruan; Yan Shi; Fan Wu
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9.  Systematic review and meta-analysis of second-generation antidepressants for the treatment of older adults with depression: questionable benefit and considerations for frailty.

Authors:  Laurie Mallery; Tanya MacLeod; Michael Allen; Pamela McLean-Veysey; Natasha Rodney-Cail; Evan Bezanson; Brian Steeves; Constance LeBlanc; Paige Moorhouse
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10.  Predicting Health with Function -  How Can Biomechanics "Ride the Tiger"?

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Journal:  J Cachexia Sarcopenia Muscle       Date:  2020-07-16       Impact factor: 12.910

  10 in total

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