| Literature DB >> 27235457 |
Pierleone Lucatelli1, Corrado Fagnani2, Adam Domonkos Tarnoki3, David Laszlo Tarnoki3, Maria Antonietta Stazi2, Miriam Salemi2, Carlo Cirelli1, Beatrice Sacconi1, Alessandro d'Adamo4, Fabrizio Fanelli1, Carlo Catalano1, Giacomo Pucci5, Giuseppe Schillaci5, Claudio Baracchini6, Emanuela Medda2.
Abstract
We compared intima-media thickness (IMT) and the prevalence of plaques in the common carotid artery (CCA) and common femoral artery (CFA) in apparently healthy participants. This multicenter study included 322 participants (59.9% female; age 20-78 years, mean 52.1 ± 15.3 years) who underwent Echo-color Doppler examination of the CCA and CFA bilaterally. Prevalence and composition of plaque were recorded. A significant ( P < .01) difference between mean CCA-IMT and mean CFA-IMT was detected (0.70 vs 0.73 mm). Plaque prevalence was significantly higher in the CFA compared to the CCA (40.7% vs 30.4%). Atherosclerotic plaques were found in both CFA and CCA in 46% of the cases, solely in CFA in 38%, and in CCA alone in 17%. The observed difference in plaque prevalence was even greater when only fibrolipid isolated plaques were considered (CFA 39.4% vs CCA 22.1%). In a healthy general population, atherosclerotic plaques were present in the CFA but not in the CCA in over one-third of the cases. Further studies must confirm whether ultrasonography of the CFA might be introduced in the screening protocols for cardiovascular risk assessment.Entities:
Keywords: cardiovascular risk; common carotid artery plaque; common femoral artery plaque; intima–media thickness
Mesh:
Year: 2016 PMID: 27235457 DOI: 10.1177/0003319716651777
Source DB: PubMed Journal: Angiology ISSN: 0003-3197 Impact factor: 3.619