Literature DB >> 27235346

Effect of chronic morphine administration on circulating dendritic cells in SIV-infected rhesus macaques.

William D Cornwell1, Wendeline Wagner2, Mark G Lewis2, Xiaoxuan Fan3, Jay Rappaport4, Thomas J Rogers5.   

Abstract

We studied the effect of chronic morphine administration on the circulating dendritic cell population dynamics associated with SIV infection using rhesus macaques. Animals were either first infected with SIV and then given chronic morphine, or visa versa. SIV infection increased the numbers of myeloid DCs (mDCs), but morphine treatment attenuated this mDC expansion. In contrast, morphine increased the numbers of plasmacytoid DCs (pDCs) in SIV-infected animals. Finally, chronic morphine administration (no SIV) transiently increased the numbers of circulating pDCs. These results show that chronic morphine induces a significant alteration in the available circulating levels of critical antigen-presenting cells.
Copyright © 2016 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  CD83; Dendritic cells; Morphine; Myeloid; Plasmacytoid; SIV

Mesh:

Substances:

Year:  2016        PMID: 27235346      PMCID: PMC4884613          DOI: 10.1016/j.jneuroim.2016.04.007

Source DB:  PubMed          Journal:  J Neuroimmunol        ISSN: 0165-5728            Impact factor:   3.478


  79 in total

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2.  Monocyte-derived CD1a+ and CD1a- dendritic cell subsets differ in their cytokine production profiles, susceptibilities to transfection, and capacities to direct Th cell differentiation.

Authors:  C C Chang; A Wright; J Punnonen
Journal:  J Immunol       Date:  2000-10-01       Impact factor: 5.422

3.  Identification of delta- and mu-type opioid receptors on human and murine dendritic cells.

Authors:  V P Makarenkova; C Esche; N V Kost; G V Shurin; B S Rabin; A A Zozulya; M R Shurin
Journal:  J Neuroimmunol       Date:  2001-07-02       Impact factor: 3.478

4.  HIV gp120 receptors on human dendritic cells.

Authors:  S G Turville; J Arthos; K M Donald; G Lynch; H Naif; G Clark; D Hart; A L Cunningham
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5.  The immunodeficiency virus coreceptor, Bonzo/STRL33/TYMSTR, is expressed by macaque and human skin- and blood-derived dendritic cells.

Authors:  R Ignatius; Y Wei; S Beaulieu; A Gettie; R M Steinman; M Pope; S Mojsov
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Review 6.  Opioids, opioid receptors, and the immune response.

Authors:  L McCarthy; M Wetzel; J K Sliker; T K Eisenstein; T J Rogers
Journal:  Drug Alcohol Depend       Date:  2001-04-01       Impact factor: 4.492

7.  Depletion in blood CD11c-positive dendritic cells from HIV-infected patients.

Authors:  F Grassi; A Hosmalin; D McIlroy; V Calvez; P Debré; B Autran
Journal:  AIDS       Date:  1999-05-07       Impact factor: 4.177

8.  Depletion of circulating natural type 1 interferon-producing cells in HIV-infected AIDS patients.

Authors:  V Soumelis; I Scott; F Gheyas; D Bouhour; G Cozon; L Cotte; L Huang; J A Levy; Y J Liu
Journal:  Blood       Date:  2001-08-15       Impact factor: 22.113

Review 9.  Cognitive function in HIV-1-infected drug users.

Authors:  G Shor-Posner
Journal:  J Acquir Immune Defic Syndr       Date:  2000-10-01       Impact factor: 3.731

10.  Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens.

Authors:  N Kadowaki; S Ho; S Antonenko; R W Malefyt; R A Kastelein; F Bazan; Y J Liu
Journal:  J Exp Med       Date:  2001-09-17       Impact factor: 14.307

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