Literature DB >> 27234816

Controlled and Sequential Delivery of Fluorophores from 3D Printed Alginate-PLGA Tubes.

Anh-Vu Do1,2, Adil Akkouch3, Brian Green2, Ibrahim Ozbolat3,4,5, Amer Debabneh3, Sean Geary1, Aliasger K Salem6,7.   

Abstract

Controlled drug delivery systems, that include sequential and/or sustained drug delivery, have been utilized to enhance the therapeutic effects of many current drugs by effectively delivering drugs in a time-dependent and repeatable manner. In this study, with the aid of 3D printing technology, a novel drug delivery device was fabricated and tested to evaluate sequential delivery functionality. With an alginate shell and a poly(lactic-co-glycolic acid) (PLGA) core, the fabricated tubes displayed sequential release of distinct fluorescent dyes and showed no cytotoxicity when incubated with the human embryonic kidney (HEK293) cell line or bone marrow stromal stem cells (BMSC). The controlled differential release of drugs or proteins through such a delivery system has the potential to be used in a wide variety of biomedical applications from treating cancer to regenerative medicine.

Entities:  

Keywords:  Alginate; Composite materials; Controlled delivery; Differential delivery; Extrusion printing; PLGA

Mesh:

Substances:

Year:  2016        PMID: 27234816      PMCID: PMC5124557          DOI: 10.1007/s10439-016-1648-9

Source DB:  PubMed          Journal:  Ann Biomed Eng        ISSN: 0090-6964            Impact factor:   4.219


  28 in total

Review 1.  3D printing in pharmaceutics: A new tool for designing customized drug delivery systems.

Authors:  Jonathan Goole; Karim Amighi
Journal:  Int J Pharm       Date:  2016-01-03       Impact factor: 5.875

Review 2.  Medication adherence in patients with rheumatoid arthritis: a critical appraisal of the existing literature.

Authors:  Bart J F van den Bemt; Hanneke E Zwikker; Cornelia H M van den Ende
Journal:  Expert Rev Clin Immunol       Date:  2012-05       Impact factor: 4.473

3.  Extrusion printed polymer structures: a facile and versatile approach to tailored drug delivery platforms.

Authors:  Parawee Rattanakit; Simon E Moulton; Karen S Santiago; Saisunee Liawruangrath; Gordon G Wallace
Journal:  Int J Pharm       Date:  2011-11-10       Impact factor: 5.875

4.  Patient medication adherence: measures in daily practice.

Authors:  Beena Jimmy; Jimmy Jose
Journal:  Oman Med J       Date:  2011-05

Review 5.  3D Printing of Scaffolds for Tissue Regeneration Applications.

Authors:  Anh-Vu Do; Behnoush Khorsand; Sean M Geary; Aliasger K Salem
Journal:  Adv Healthc Mater       Date:  2015-06-10       Impact factor: 9.933

6.  3D printing of modified-release aminosalicylate (4-ASA and 5-ASA) tablets.

Authors:  Alvaro Goyanes; Asma B M Buanz; Grace B Hatton; Simon Gaisford; Abdul W Basit
Journal:  Eur J Pharm Biopharm       Date:  2014-12-09       Impact factor: 5.571

7.  Bioerodible system for sequential release of multiple drugs.

Authors:  Sharath C Sundararaj; Mark V Thomas; Thomas D Dziubla; David A Puleo
Journal:  Acta Biomater       Date:  2013-10-01       Impact factor: 8.947

8.  The enhancement of bone regeneration by gene activated matrix encoding for platelet derived growth factor.

Authors:  Satheesh Elangovan; Sheetal R D'Mello; Liu Hong; Ryan D Ross; Chantal Allamargot; Deborah V Dawson; Clark M Stanford; Georgia K Johnson; D Rick Sumner; Aliasger K Salem
Journal:  Biomaterials       Date:  2013-10-22       Impact factor: 12.479

9.  On-demand drug release system for in vivo cancer treatment through self-assembled magnetic nanoparticles.

Authors:  Jae-Hyun Lee; Kuan-Ju Chen; Seung-Hyun Noh; Mitch André Garcia; Hao Wang; Wei-Yu Lin; Heeyeong Jeong; Brian Junoh Kong; David B Stout; Jinwoo Cheon; Hsian-Rong Tseng
Journal:  Angew Chem Int Ed Engl       Date:  2013-03-20       Impact factor: 15.336

10.  Chemically modified RNA activated matrices enhance bone regeneration.

Authors:  Satheesh Elangovan; Behnoush Khorsand; Anh-Vu Do; Liu Hong; Alexander Dewerth; Michael Kormann; Ryan D Ross; D Rick Sumner; Chantal Allamargot; Aliasger K Salem
Journal:  J Control Release       Date:  2015-09-28       Impact factor: 11.467

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  12 in total

1.  3D printing in drug delivery systems.

Authors:  Jaidev L Chakka; Aliasger K Salem
Journal:  J 3D Print Med       Date:  2019-05-31

2.  Controlled drug delivery from 3D printed two-photon polymerized poly(ethylene glycol) dimethacrylate devices.

Authors:  Anh-Vu Do; Kristan S Worthington; Budd A Tucker; Aliasger K Salem
Journal:  Int J Pharm       Date:  2018-09-27       Impact factor: 5.875

Review 3.  3D Bioprinting for Organ Regeneration.

Authors:  Haitao Cui; Margaret Nowicki; John P Fisher; Lijie Grace Zhang
Journal:  Adv Healthc Mater       Date:  2016-12-20       Impact factor: 9.933

Review 4.  Advances in three-dimensional bioprinted stem cell-based tissue engineering for cardiovascular regeneration.

Authors:  Astha Khanna; Bugra Ayan; Ada A Undieh; Yunzhi P Yang; Ngan F Huang
Journal:  J Mol Cell Cardiol       Date:  2022-05-12       Impact factor: 5.763

5.  3D Coaxial Bioprinting: Process Mechanisms, Bioinks and Applications.

Authors:  Tarun Shyam Mohan; Pallab Datta; Sepehr Nesaei; Veli Ozbolat; Ibrahim T Ozbolat
Journal:  Prog Biomed Eng (Bristol)       Date:  2022-04-20

Review 6.  An updated review on application of 3D printing in fabricating pharmaceutical dosage forms.

Authors:  Rabinarayan Parhi; Goutam Kumar Jena
Journal:  Drug Deliv Transl Res       Date:  2021-10-06       Impact factor: 5.671

7.  Expanding sacrificially printed microfluidic channel-embedded paper devices for construction of volumetric tissue models in vitro.

Authors:  Hongbin Li; Feng Cheng; Wanlu Li; Xia Cao; Zixuan Wang; Mian Wang; Juan Antonio Robledo-Lara; Junlong Liao; Carolina Chávez-Madero; Shabir Hassan; Jingwei Xie; Grissel Trujillo-de Santiago; Mario Moisés Álvarez; Jinmei He; Yu Shrike Zhang
Journal:  Biofabrication       Date:  2020-09-18       Impact factor: 9.954

Review 8.  Nanogels for Pharmaceutical and Biomedical Applications and Their Fabrication Using 3D Printing Technologies.

Authors:  Hyunah Cho; Udayabhanu Jammalamadaka; Karthik Tappa
Journal:  Materials (Basel)       Date:  2018-02-16       Impact factor: 3.623

Review 9.  Bone Regeneration Using Gene-Activated Matrices.

Authors:  Sheetal D'Mello; Keerthi Atluri; Sean M Geary; Liu Hong; Satheesh Elangovan; Aliasger K Salem
Journal:  AAPS J       Date:  2016-09-21       Impact factor: 3.603

Review 10.  Bioinks and bioprinting technologies to make heterogeneous and biomimetic tissue constructs.

Authors:  N Ashammakhi; S Ahadian; C Xu; H Montazerian; H Ko; R Nasiri; N Barros; A Khademhosseini
Journal:  Mater Today Bio       Date:  2019-05-25
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