| Literature DB >> 2723442 |
J P Kints1, P Manouvriez, H Bazin.
Abstract
The effect of intraperitoneal injections of pristane, incomplete Freund's adjuvant (IFA) and a v/v mixture of pristane and IFA (called PIFA) on ascites production and the yield of monoclonal antibodies has been studied in Louvain rats. The best results were obtained following injection of 2 ml PIFA at the moment of i.p. transfer of hybridoma or immunocytoma cells. Ascites production was increased by as much as 4.7 times and monoclonal antibody production by more than six times compared with untreated control rats.Entities:
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Year: 1989 PMID： 2723442 DOI： 10.1016/0022-1759(89)90402-x
Source DB: PubMed Journal: J Immunol Methods ISSN： 0022-1759 Impact factor: 2.303