Benedikt M Schaarschmidt1, Lino M Sawicki2, Benedikt Gomez3, Johannes Grueneisen4, Mathias Hoiczyk5, Philipp Heusch2, Christian Buchbender2. 1. University Dusseldorf, Medical Faculty, Department of Diagnostic and Interventional Radiology, D-40225 Dusseldorf, Germany; University Duisburg-Essen, Medical Faculty, Department of Diagnostic and Interventional Radiology and Neuroradiology, D-45147 Essen, Germany. Electronic address: Benedikt.Schaarschmidt@med.uni-duesseldorf.de. 2. University Dusseldorf, Medical Faculty, Department of Diagnostic and Interventional Radiology, D-40225 Dusseldorf, Germany. 3. University Duisburg-Essen, Medical Faculty, Department of Nuclear Medicine, D-45147 Essen, Germany. 4. University Duisburg-Essen, Medical Faculty, Department of Diagnostic and Interventional Radiology and Neuroradiology, D-45147 Essen, Germany. 5. University Duisburg-Essen, Medical Faculty, Department of Medical Oncology, Essen, Germany.
Abstract
PURPOSE: This study aims to compare staging results of (18)F-FDG PET/computed tomography (CT) and integrated PET/magnetic resonance (MR) in malignant pleural mesothelioma (MPM) patients and to investigate a potential apparent diffusion coefficient (ADC)/SUV correlation. MATERIALS AND METHODS: Six patients with MPM underwent (18)F-FDG PET/CT and PET/MR including diffusion-weighted imaging. Thoracic TNM staging was performed for both modalities. SUV and ADC were assessed in therapy-naive pleural lesions. RESULTS: In thoracic TNM staging, no differences were found between PET/CT and PET/MR. An inverse correlation was observed between SUVmean and ADCmin (r=-0.63, P=.002). CONCLUSION: MPM can be staged using PET/MR. The inverse correlation ADC/SUV indicates that future research on multiparametric therapy response evaluation may be warranted.
PURPOSE: This study aims to compare staging results of (18)F-FDG PET/computed tomography (CT) and integrated PET/magnetic resonance (MR) in malignant pleural mesothelioma (MPM) patients and to investigate a potential apparent diffusion coefficient (ADC)/SUV correlation. MATERIALS AND METHODS: Six patients with MPM underwent (18)F-FDG PET/CT and PET/MR including diffusion-weighted imaging. Thoracic TNM staging was performed for both modalities. SUV and ADC were assessed in therapy-naive pleural lesions. RESULTS: In thoracic TNM staging, no differences were found between PET/CT and PET/MR. An inverse correlation was observed between SUVmean and ADCmin (r=-0.63, P=.002). CONCLUSION: MPM can be staged using PET/MR. The inverse correlation ADC/SUV indicates that future research on multiparametric therapy response evaluation may be warranted.
Authors: L Kamper; N M Dreger; A S Brandt; T Pöppel; N Abanador-Kamper; S Roth; P Haage Journal: Int J Cardiovasc Imaging Date: 2018-06-15 Impact factor: 2.357
Authors: D L Bailey; B J Pichler; B Gückel; G Antoch; H Barthel; Z M Bhujwalla; S Biskup; S Biswal; M Bitzer; R Boellaard; R F Braren; C Brendle; K Brindle; A Chiti; C la Fougère; R Gillies; V Goh; M Goyen; M Hacker; L Heukamp; G M Knudsen; A M Krackhardt; I Law; J C Morris; K Nikolaou; J Nuyts; A A Ordonez; K Pantel; H H Quick; K Riklund; O Sabri; B Sattler; E G C Troost; M Zaiss; L Zender; Thomas Beyer Journal: Mol Imaging Biol Date: 2018-02 Impact factor: 3.488