Literature DB >> 27231687

Conjunctival Angioimmunoblastic T-Cell Lymphoma.

Darshak S Patel1, Paul Rundle1, Sachin M Salvi1, Malee Fernando2, Hardeep Singh Mudhar3.   

Abstract

Angioimmunoblastic T-cell lymphoma (AITL) represents an uncommon variant of T-cell lymphomas and most often presents insidiously with systemic symptoms. This report constitutes the first documented case of conjunctival AITL, masquerading as nodular episcleritis, and describes both the clinical and pathological findings. Furthermore, conjunctival T-cell lymphoma in general remains a rare occurrence, and a survey of previously reported cases reveals a wide variation in clinical presentation. A high index of suspicion, thorough examination and conjunctival biopsy are essential to reaching the diagnosis of conjunctival lymphoma.

Entities:  

Keywords:  Angioimmunoblastic T-cell lymphoma; Conjunctiva; Differential diagnosis; Epstein-Barr virus; Nodular episcleritis

Year:  2014        PMID: 27231687      PMCID: PMC4873707          DOI: 10.1159/000368247

Source DB:  PubMed          Journal:  Ocul Oncol Pathol        ISSN: 2296-4657


  17 in total

1.  T-cell and T/natural killer-cell lymphomas involving ocular and ocular adnexal tissues: a clinicopathologic, immunohistochemical, and molecular study of seven cases.

Authors:  S E Coupland; H D Foss; C Assaf; C Auw-Haedrich; G Anastassiou; I Anagnostopoulos; M Hummel; J W Karesh; W R Lee; H Stein
Journal:  Ophthalmology       Date:  1999-11       Impact factor: 12.079

2.  Clinicopathologic reports, case reports, and small case series: rapidly progressive T-cell lymphoma of the conjunctiva.

Authors:  Carol L Shields; Jerry A Shields; Ralph C Eagle
Journal:  Arch Ophthalmol       Date:  2002-04

3.  Multifocal nodular episcleritis and scleritis with undiagnosed Hodgkin's lymphoma.

Authors:  Manoj M Thakker; Victor L Perez; Alexandre Moulin; Sandra L Cremers; C Stephen Foster
Journal:  Ophthalmology       Date:  2003-05       Impact factor: 12.079

4.  Characterization of lymphoproliferative lesions of the conjunctiva: immunohistochemical and molecular genetic studies.

Authors:  James P Farmer; Manisha Lamba; Andrew B Merkur; Wiplove R Lamba; William G Hodge; David R Jordan; Dharmendra P S Sengar; Bruce F Burns
Journal:  Can J Ophthalmol       Date:  2006-12       Impact factor: 1.882

5.  Conjunctival lymphoid tumors: clinical analysis of 117 cases and relationship to systemic lymphoma.

Authors:  C L Shields; J A Shields; C Carvalho; P Rundle; A F Smith
Journal:  Ophthalmology       Date:  2001-05       Impact factor: 12.079

6.  Clinicopathologic, immunophenotypic, and immunogenotypic analyses of immunoblastic lymphadenopathy-like T-cell lymphoma.

Authors:  K Tobinai; K Minato; T Ohtsu; K Mukai; Y Kagami; M Miwa; S Watanabe; M Shimoyama
Journal:  Blood       Date:  1988-09       Impact factor: 22.113

7.  Conjunctival T-cell lymphoma: a clinicopathologic case report.

Authors:  Abdulrahman Al-Muammar; William G Hodge; James Farmer
Journal:  Ophthalmology       Date:  2006-01-20       Impact factor: 12.079

8.  T-cell malignant lymphoma with conjunctival involvement.

Authors:  F R Hu; J C Lin; I P Chiang; K H Yeh
Journal:  Am J Ophthalmol       Date:  1998-05       Impact factor: 5.258

9.  Peripheral T-cell lymphoma presenting as sclerouveitis.

Authors:  Thomas J Kirn; Norman B Levy; J J Benoit Gosselin; William J Rosen; Michael E Zegans
Journal:  Cornea       Date:  2007-10       Impact factor: 2.651

10.  Angioimmunoblastic lymphadenopathy. Long-term follow-up study.

Authors:  G A Pangalis; E M Moran; B N Nathwani; R J Zelman; H Kim; H Rappaport
Journal:  Cancer       Date:  1983-07-15       Impact factor: 6.860

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