Swetha Dhanireddy1,2, Ninani C Kombo1,2,3, Abhishek R Payal1,2, Clovis Arcoverde Freitas-Neto1,2,4, Janine Preble1,2, C Stephen Foster1,2,5. 1. a Massachusetts Eye Research and Surgery Institution , Waltham , Massachusetts , USA. 2. b Ocular Immunology and Uveitis Foundation , Waltham , Massachusetts , USA. 3. d Yale School of Medicine , New Haven , Connecticut , USA. 4. c Hospital de Olhos Santa Luzia, Recife , Pernambuco , Brazil. 5. e Harvard Medical School , Boston , Massachusetts , USA.
Abstract
PURPOSE: To evaluate the outcomes of the Ex-PRESS Filtration Device in patients with uveitic glaucoma. METHODS: We reviewed 23 eyes, comparing control simple glaucoma patients (n = 11) to uveitic glaucoma patients (n = 12). Intraocular pressure (IOP) and glaucoma medications at the preoperative examination were compared with those at the 6-month and 10-14-month postoperative examination. Surgical success was defined as ≥25% decrease in intraocular pressure without hypotony, and/or decrease in glaucoma medications at 6 months follow-up. RESULTS: Statistically significant reduction in mean IOP from preoperative levels occurred in both groups at 6 months follow-up (p<0.0001) and 10-14 months follow-up (p = 0.0007) and in the mean number of medications in the uveitic glaucoma (UG) group (p = 0.0313). CONCLUSIONS: Surgical success was seen in 10 eyes in the control group (90.9%) and nine eyes (75%) in the UG group (p = 0.314). Ex-PRESS implantation is an effective surgical intervention for the management of uveitic glaucoma.
PURPOSE: To evaluate the outcomes of the Ex-PRESS Filtration Device in patients with uveitic glaucoma. METHODS: We reviewed 23 eyes, comparing control simple glaucomapatients (n = 11) to uveitic glaucomapatients (n = 12). Intraocular pressure (IOP) and glaucoma medications at the preoperative examination were compared with those at the 6-month and 10-14-month postoperative examination. Surgical success was defined as ≥25% decrease in intraocular pressure without hypotony, and/or decrease in glaucoma medications at 6 months follow-up. RESULTS: Statistically significant reduction in mean IOP from preoperative levels occurred in both groups at 6 months follow-up (p<0.0001) and 10-14 months follow-up (p = 0.0007) and in the mean number of medications in the uveitic glaucoma (UG) group (p = 0.0313). CONCLUSIONS: Surgical success was seen in 10 eyes in the control group (90.9%) and nine eyes (75%) in the UG group (p = 0.314). Ex-PRESS implantation is an effective surgical intervention for the management of uveitic glaucoma.
Authors: Nestor Ventura-Abreu; Joana Mendes-Pereira; Marta Pazos; Ma Jesús Muniesa-Royo; Andrea Gonzalez-Ventosa; Barbara Romero-Nuñez; Elena Milla Journal: J Curr Glaucoma Pract Date: 2021 May-Aug