Literature DB >> 2722762

Molecular cloning and sequence analysis of cDNA containing the entire coding region for human fetal liver cytochrome P-450.

M Komori1, K Nishio, H Ohi, M Kitada, T Kamataki.   

Abstract

From a human fetal liver cDNA library, a cDNA clone (lambda HFL33) containing the entire coding region for a form of cytochrome P-450 related to P-450 HFLa was obtained. The clone was 1,971 bp long and had an open reading frame of 1,509 nucleotides coding for a 503 amino acid polypeptide. The nucleotide and the deduced amino acid sequences of lambda HFL33 were very similar to but clearly distinct from those of NF25 and HLp cDNAs, which code for forms of cytochrome P-450 in adult human liver. The deduced N-terminal amino acid sequence of the HFL33 protein was identical to that of P-450 HFLa.

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Year:  1989        PMID: 2722762     DOI: 10.1093/oxfordjournals.jbchem.a122632

Source DB:  PubMed          Journal:  J Biochem        ISSN: 0021-924X            Impact factor:   3.387


  15 in total

1.  New nucleotide sequence data on the EMBL File Server.

Authors: 
Journal:  Nucleic Acids Res       Date:  1990-10-25       Impact factor: 16.971

Review 2.  Cytochrome P450 3A: ontogeny and drug disposition.

Authors:  S N de Wildt; G L Kearns; J S Leeder; J N van den Anker
Journal:  Clin Pharmacokinet       Date:  1999-12       Impact factor: 6.447

Review 3.  Neonatal cytochrome P450 CYP3A7: A comprehensive review of its role in development, disease, and xenobiotic metabolism.

Authors:  Haixing Li; Jed N Lampe
Journal:  Arch Biochem Biophys       Date:  2019-08-22       Impact factor: 4.013

4.  Expression of cytochrome P 450 3A enzymes in human lung: a combined RT-PCR and immunohistochemical analysis of normal tissue and lung tumours.

Authors:  K T Kivistö; E U Griese; P Fritz; A Linder; J Hakkola; H Raunio; P Beaune; H K Kroemer
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1996-01       Impact factor: 3.000

Review 5.  The influence of age and sex on the clearance of cytochrome P450 3A substrates.

Authors:  Monette M Cotreau; Lisa L von Moltke; David J Greenblatt
Journal:  Clin Pharmacokinet       Date:  2005       Impact factor: 6.447

6.  Comparison of urinary 6beta-hydroxycortisol/cortisol ratio between neonates and their mothers.

Authors:  H Nakamura; A Hasegawa; M Kimura; S Yamagata; H Nakasa; H Osada; S Sekiya; S Ohmori; M Kitada
Journal:  Br J Clin Pharmacol       Date:  1999-01       Impact factor: 4.335

7.  Identification of the fetal liver cytochrome CYP3A7 in human endometrium and placenta.

Authors:  J D Schuetz; S Kauma; P S Guzelian
Journal:  J Clin Invest       Date:  1993-08       Impact factor: 14.808

8.  Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes.

Authors:  J C Kolars; P Schmiedlin-Ren; J D Schuetz; C Fang; P B Watkins
Journal:  J Clin Invest       Date:  1992-11       Impact factor: 14.808

Review 9.  P450 enzymes. Inhibition mechanisms, genetic regulation and effects of liver disease.

Authors:  M Murray
Journal:  Clin Pharmacokinet       Date:  1992-08       Impact factor: 6.447

Review 10.  Developmental changes in the expression and function of cytochrome P450 3A isoforms: evidence from in vitro and in vivo investigations.

Authors:  Ibrahim Ince; Catherijne A J Knibbe; Meindert Danhof; Saskia N de Wildt
Journal:  Clin Pharmacokinet       Date:  2013-05       Impact factor: 6.447

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