Literature DB >> 27224929

Radiation dose distribution in the teeth, maxilla, and mandible of patients with oropharyngeal and nasopharyngeal tumors who were treated with intensity-modulated radiotherapy.

Cláudia Joffily Parahyba1, Fábio Ynoe Moraes2, Pedro Augusto Minorim Ramos3, Cecília Maria Kalil Haddad3, João Luis Fernandes da Silva2, Eduardo Rodrigues Fregnani4.   

Abstract

BACKGROUND: The purpose of this study was to evaluate the distribution of the intensity-modulated radiotherapy (IMRT) dose delivered to the teeth, maxilla, and mandible.
METHODS: The mean dose (Dmean) and maximum dose (Dmax) of radiation for the maxilla, mandible, and teeth of 63 patients with oropharyngeal (n = 44) or nasopharyngeal (n = 19) tumors were retrospectively evaluated.
RESULTS: The posterior regions of the mandible received the highest doses, and the teeth received lower doses than the bones (maximum dose, p < .001; average dose, p < .001). The Dmax (p < .001) and Dmean (p < .001) depended on primary tumor location. The superior bones and teeth of patients with nasopharyngeal tumors received more radiation than those of patients with oropharyngeal tumors.
CONCLUSION: A dose distribution map was generated based on the estimated doses received, which could allow prediction of the areas most affected by radiation and facilitate further correlations with dental complications after radiotherapy.
© 2016 Wiley Periodicals, Inc. Head Neck 38: 1708-1716, 2016. © 2016 Wiley Periodicals, Inc.

Entities:  

Keywords:  dosimetry; head and neck cancer; radiotherapy

Mesh:

Year:  2016        PMID: 27224929     DOI: 10.1002/hed.24479

Source DB:  PubMed          Journal:  Head Neck        ISSN: 1043-3074            Impact factor:   3.147


  3 in total

1.  Leukocyte- and platelet-rich fibrin as an adjuvant to the surgical approach for osteoradionecrosis: a case report.

Authors:  Gustavo Maluf; Rogério Jardim Caldas; Eduardo Rodrigues Fregnani; Paulo Sérgio da Silva Santos
Journal:  J Korean Assoc Oral Maxillofac Surg       Date:  2020-04-30

2.  Dosimetric Comparison between Volumetric Modulated Arc Therapy (VMAT) and Intensity-Modulated Radiotherapy (IMRT) for Dental Structures of Head and Neck Cancer Patients.

Authors:  Yan Ma; Jianfeng Zhou; Hongyong Wang
Journal:  J Healthc Eng       Date:  2022-04-05       Impact factor: 2.682

3.  IMRT delivers lower radiation doses to dental structures than 3DRT in head and neck cancer patients.

Authors:  Eduardo Rodrigues Fregnani; Cláudia Joffily Parahyba; Karina Morais-Faria; Felipe Paiva Fonseca; Pedro Augusto Mendes Ramos; Fábio Yone de Moraes; Karina Gondim Moutinho da Conceição Vasconcelos; Gisela Menegussi; Alan Roger Santos-Silva; Thais B Brandão
Journal:  Radiat Oncol       Date:  2016-09-07       Impact factor: 3.481

  3 in total

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