Literature DB >> 27224077

Assessment of surgical outcomes of limbal transplantation using simple limbal epithelial transplantation technique in patients with total unilateral limbal deficiency.

Ana Gabriela Queiroz1, Martina Maria Oiticica Barbosa1, Myrna Serapião Santos2, Telma Pereira Barreiro2, José Álvaro Pereira Gomes2.   

Abstract

This study aimed to evaluate the effectiveness of the novel simple limbal epithelial transplantation (SLET) technique, which reduces the risk of iatrogenic limbal stem cell deficiency in the donor eye. Four patients with total unilateral limbal stem cell deficiency received a limbal graft, measuring 4 mm × 2 mm, from the contralateral healthy eye in a single surgical procedure. The graft was divided into 10-20 pieces and distributed on the corneal surface. At 6-month follow-up, a completely avascular corneal epithelial surface was obtained in two patients, and there was improvement in visual acuity in one patient. The limbal grafts did not adhere to the cornea in one patient. No serious complications related to the surgery were observed in this study.

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Year:  2016        PMID: 27224077     DOI: 10.5935/0004-2749.20160034

Source DB:  PubMed          Journal:  Arq Bras Oftalmol        ISSN: 0004-2749            Impact factor:   0.872


  6 in total

1.  Outcomes of deep anterior lamellar keratoplasty following autologous simple limbal epithelial transplant in pediatric unilateral severe chemical injury.

Authors:  Divya Singh; M Vanathi; Chanchal Gupta; Noopur Gupta; Radhika Tandon
Journal:  Indian J Ophthalmol       Date:  2017-03       Impact factor: 1.848

Review 2.  Twenty years of limbal epithelial therapy: an update on managing limbal stem cell deficiency.

Authors:  Roberto Fernandez-Buenaga; Francesco Aiello; Sarah S Zaher; Andre Grixti; Sajjad Ahmad
Journal:  BMJ Open Ophthalmol       Date:  2018-08-10

Review 3.  Simple limbal epithelial transplantation (SLET): Review of indications, surgical technique, mechanism, outcomes, limitations, and impact.

Authors:  Swapna S Shanbhag; Chaitali N Patel; Ritin Goyal; Pragnya R Donthineni; Vivek Singh; Sayan Basu
Journal:  Indian J Ophthalmol       Date:  2019-08       Impact factor: 1.848

Review 4.  Simple limbal epithelial transplantation: Current status and future perspectives.

Authors:  Catherine J Jackson; Inger T Myklebust Ernø; Håkon Ringstad; Kim A Tønseth; Darlene A Dartt; Tor P Utheim
Journal:  Stem Cells Transl Med       Date:  2019-12-04       Impact factor: 6.940

Review 5.  Current perspectives of limbal-derived stem cells and its application in ocular surface regeneration and limbal stem cell transplantation.

Authors:  Vivek Singh; Anil Tiwari; Abhinav Reddy Kethiri; Virender Singh Sangwan
Journal:  Stem Cells Transl Med       Date:  2021-05-05       Impact factor: 6.940

Review 6.  Economic, clinical and social impact of simple limbal epithelial transplantation for limbal stem cell deficiency.

Authors:  Praveen Thokala; Aastha Singh; Vijay Kumar Singh; Varsha M Rathi; Sayan Basu; Vivek Singh; Sheila MacNeil; Virender Singh Sangwan
Journal:  Br J Ophthalmol       Date:  2021-03-09       Impact factor: 5.908

  6 in total

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