Richard C Semelka1, Miguel Ramalho1,2, Mamdoh AlObaidy1,3, Joana Ramalho1,4. 1. 1 Department of Radiology, University of North Carolina at Chapel Hill, CB 7510 - 2001 Old Clinic Bldg, 101 Manning Dr, Chapel Hill, NC 27599-7510. 2. 2 Department of Radiology, Hospital Garcia de Orta, Almada, Portugal. 3. 3 Department of Radiology. King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia. 4. 4 Department of Neuroradiology, Centro Hospitalar de Lisboa Central, Lisbon, Portugal.
Abstract
OBJECTIVE: The literature informs us that gadolinium can cause health issues. At least four major gadolinium disorders, including the two well-recognized nephrogenic systemic fibrosis and severe acute adverse event, have been identified. CONCLUSION: We propose naming the histopathologically proven presence of gadolinium in brain tissue "gadolinium storage condition," and we describe a new entity that represents symptomatic deposition of gadolinium in individuals with normal renal function, for which we propose the designation "gadolinium deposition disease."
OBJECTIVE: The literature informs us that gadolinium can cause health issues. At least four major gadolinium disorders, including the two well-recognized nephrogenic systemic fibrosis and severe acute adverse event, have been identified. CONCLUSION: We propose naming the histopathologically proven presence of gadolinium in brain tissue "gadolinium storage condition," and we describe a new entity that represents symptomatic deposition of gadolinium in individuals with normal renal function, for which we propose the designation "gadoliniumdeposition disease."
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