Literature DB >> 27222931

Isoform-Selective HDAC Inhibitor Therapy for Transplantation: Are We Ready for HDAC6?

Wayne W Hancock1.   

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Year:  2016        PMID： 27222931      PMCID： PMC4961515          DOI： 10.1097/TP.0000000000001209

Source DB:  PubMed          Journal:  Transplantation        ISSN： 0041-1337            Impact factor:   4.939


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  11 in total

1.  Thiol-Based Potent and Selective HDAC6 Inhibitors Promote Tubulin Acetylation and T-Regulatory Cell Suppressive Function.

Authors:  Mariana C F Segretti; Gian Paolo Vallerini; Camille Brochier; Brett Langley; Liqing Wang; Wayne W Hancock; Alan P Kozikowski
Journal:  ACS Med Chem Lett       Date:  2015-10-05       Impact factor: 4.345

Review 2.  Hurdles in therapy with regulatory T cells.

Authors:  Piotr Trzonkowski; Rosa Bacchetta; Manuela Battaglia; David Berglund; Hermann Richard Bohnenkamp; Anja ten Brinke; Andrew Bushell; Nathalie Cools; Edward K Geissler; Silvia Gregori; S Marieke van Ham; Catharien Hilkens; James A Hutchinson; Giovanna Lombardi; J Alejandro Madrigal; Natalia Marek-Trzonkowska; Eva M Martinez-Caceres; Maria Grazia Roncarolo; Silvia Sanchez-Ramon; Aurore Saudemont; Birgit Sawitzki
Journal:  Sci Transl Med       Date:  2015-09-09       Impact factor: 17.956

3.  Inhibition of HDAC9 increases T regulatory cell function and prevents colitis in mice.

Authors:  Edwin F de Zoeten; Liqing Wang; Hong Sai; Wolfgang H Dillmann; Wayne W Hancock
Journal:  Gastroenterology       Date:  2009-10-29       Impact factor: 22.682

4.  Histone deacetylase 6 and heat shock protein 90 control the functions of Foxp3(+) T-regulatory cells.

Authors:  Edwin F de Zoeten; Liqing Wang; Kyle Butler; Ulf H Beier; Tatiana Akimova; Hong Sai; James E Bradner; Ralph Mazitschek; Alan P Kozikowski; Patrick Matthias; Wayne W Hancock
Journal:  Mol Cell Biol       Date:  2011-03-28       Impact factor: 4.272

5.  Histone deacetylases 6 and 9 and sirtuin-1 control Foxp3+ regulatory T cell function through shared and isoform-specific mechanisms.

Authors:  Ulf H Beier; Liqing Wang; Rongxiang Han; Tatiana Akimova; Yujie Liu; Wayne W Hancock
Journal:  Sci Signal       Date:  2012-06-19       Impact factor: 8.192

6.  Lysine acetylation targets protein complexes and co-regulates major cellular functions.

Authors:  Chunaram Choudhary; Chanchal Kumar; Florian Gnad; Michael L Nielsen; Michael Rehman; Tobias C Walther; Jesper V Olsen; Matthias Mann
Journal:  Science       Date:  2009-07-16       Impact factor: 47.728

7.  Deacetylase inhibition promotes the generation and function of regulatory T cells.

Authors:  Ran Tao; Edwin F de Zoeten; Engin Ozkaynak; Chunxia Chen; Liqing Wang; Paige M Porrett; Bin Li; Laurence A Turka; Eric N Olson; Mark I Greene; Andrew D Wells; Wayne W Hancock
Journal:  Nat Med       Date:  2007-10-07       Impact factor: 53.440

8.  Why Hydroxamates May Not Be the Best Histone Deacetylase Inhibitors--What Some May Have Forgotten or Would Rather Forget?

Authors:  Sida Shen; Alan P Kozikowski
Journal:  ChemMedChem       Date:  2015-11-25       Impact factor: 3.466

9.  Inhibition of Histone Deacetylase 6 Reveals a Potent Immunosuppressant Effect in Models of Transplantation.

Authors:  Jonathan D Ellis; Desley A H Neil; Nick G Inston; Eric Jenkinson; Mark T Drayson; Peter Hampson; Stephen J Shuttleworth; Andrew R Ready; Mark Cobbold
Journal:  Transplantation       Date:  2016-08       Impact factor: 4.939

Review 10.  The many roles of histone deacetylases in development and physiology: implications for disease and therapy.

Authors:  Michael Haberland; Rusty L Montgomery; Eric N Olson
Journal:  Nat Rev Genet       Date:  2009-01       Impact factor: 53.242
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  2 in total

Review 1.  Histone/protein deacetylase inhibitor therapy for enhancement of Foxp3+ T-regulatory cell function posttransplantation.

Authors:  L Wang; U H Beier; T Akimova; S Dahiya; R Han; A Samanta; M H Levine; W W Hancock
Journal:  Am J Transplant       Date:  2018-04-21       Impact factor: 8.086

2.  HDAC10 deletion promotes Foxp3+ T-regulatory cell function.

Authors:  Satinder Dahiya; Ulf H Beier; Liqing Wang; Rongxiang Han; Jing Jiao; Tatiana Akimova; Alessia Angelin; Douglas C Wallace; Wayne W Hancock
Journal:  Sci Rep       Date:  2020-01-16       Impact factor: 4.379
  2 in total

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