Literature DB >> 27222649

Long-term Survival From Muscleinvasive Bladder Cancer With Initial Presentation of Symptomatic Cerebellar Lesion: The Role of Selective Surgical Extirpation of the Primary and Metastatic Lesion.

Ganesh K Kartha1, Joseph Sanfrancesco2, Esther Udoji3, Hemant Chaparala4, Donna Hansel2, J Stephen Jones1.   

Abstract

A 59-year-old man was diagnosed with urothelial carcinoma involving an isolated cerebellar metastasis after presenting to the emergency department for headache complaints. After selective surgical excision of the symptomatic brain lesion and delayed cystectomy due to intractable hematuria, he survived 11 years without evidence of recurrence or subsequent systemic chemotherapy. He eventually expired after delayed recurrence in the lung, supraclavicular lymph node, and brain. To our knowledge, this is the only case of prolonged survival from urothelial carcinoma after selective surgical extirpation of the primary and metastatic lesion without subsequent systemic chemotherapy.

Entities:  

Keywords:  Bladder cancer; Cystectomy; Metastasis; Urothelial carcinoma

Year:  2015        PMID: 27222649      PMCID: PMC4857904          DOI: 10.3909/riu0643

Source DB:  PubMed          Journal:  Rev Urol        ISSN: 1523-6161


  8 in total

1.  Urinary bladder carcinoma initially manifested as brain metastases.

Authors:  C M Quinn; H Thomas; M B Prentice
Journal:  Postgrad Med J       Date:  1992-08       Impact factor: 2.401

2.  Urinary bladder carcinoma initially manifested as brain metastases.

Authors:  J C Angulo; J I López; M Unda-Urzaiz; N Flores
Journal:  Postgrad Med J       Date:  1992-02       Impact factor: 2.401

3.  Assessment and management of deeply invasive and metastatic lesions.

Authors:  W F Whitmore
Journal:  Cancer Res       Date:  1977-08       Impact factor: 12.701

4.  Brain metastases from bladder carcinoma: presentation, treatment and survival.

Authors:  Ashraf S Mahmoud-Ahmed; John H Suh; Patrick A Kupelian; Eric A Klein; David M Peereboom; Robert Dreicer; Gene H Barnett
Journal:  J Urol       Date:  2002-06       Impact factor: 7.450

Review 5.  Solitary cerebellar metastasis from transitional cell carcinoma of bladder.

Authors:  G J Shamdas; G D McLaren; T Grimm; L K Everson
Journal:  Urology       Date:  1992-07       Impact factor: 2.649

6.  Large cerebellar lesion as original manifestation of transitional cell carcinoma of the bladder.

Authors:  Benjamin J Davies; Sheldon Bastacky; Steve Y Chung
Journal:  Urology       Date:  2003-10       Impact factor: 2.649

7.  Treatment of brain metastases from bladder cancer.

Authors:  M Rosenstein; K Wallner; H Scher; C N Sternberg
Journal:  J Urol       Date:  1993-03       Impact factor: 7.450

8.  High incidence of brain metastases in patients treated with an M-VAC regimen for advanced bladder cancer.

Authors:  R Dhote; P Beuzeboc; N Thiounn; T Flam; M Zerbib; B Christoforov; B Debré
Journal:  Eur Urol       Date:  1998       Impact factor: 20.096

  8 in total
  1 in total

1.  Central Nervous System Metastasis in Patients With Urothelial Carcinoma: Institutional Experience and a Comprehensive Review of the Literature.

Authors:  Leonidas N Diamantopoulos; Ali R Khaki; Guru P Sonpavde; Vyshak A Venur; Evan Y Yu; Jonathan L Wright; Petros Grivas
Journal:  Clin Genitourin Cancer       Date:  2019-12-05       Impact factor: 2.872

  1 in total

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