| Literature DB >> 27221493 |
Vincent Compan1,2, Gloria López-Castejón3.
Abstract
Inflammasomes are molecular complexes that initiate innate immune response. They are mainly expressed by immune cells; however, molecular manipulations in these cells remain very difficult. Here, we describe a simple protocol to overexpress and activate functional NRLP3 inflammasomes in HEK293 cells.Keywords: ASC; Active caspase-1; HEK293; Inflammasome; NLR
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Year: 2016 PMID： 27221493 DOI： 10.1007/978-1-4939-3566-6_15
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745