Literature DB >> 27220544

Clinical effects of liraglutide are possibly influenced by hypertriglyceridemia and remaining pancreatic β-cell function in subjects with type 2 diabetes mellitus.

Akihito Tanabe1, Hideaki Kaneto1, Shinji Kamei2, Hidenori Hirukawa1, Masashi Shimoda1, Tomohiko Kimura1, Atsushi Obata1, Seizo Okauchi1, Fuminori Tatsumi1, Kenji Kohara1, Tomoatsu Mune1, Kohei Kaku1.   

Abstract

We searched for factors influencing the clinical effects of GLP-1 analogue liraglutide in subjects with type 2 diabetes. Multivariate analyses showed that hypertriglyceridemia and baseline HbA1c levels were independent predictors for the efficacy of liraglutide and that CPR index was an independent predictor for the durability of liraglutide.
Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Liraglutide; Llipid control; Pancreatic β-cell function

Mesh：

Substances：

Year:  2016        PMID： 27220544     DOI： 10.1016/j.jdiacomp.2016.04.005

Source DB:  PubMed          Journal:  J Diabetes Complications        ISSN： 1056-8727            Impact factor:   2.852


  3 in total

1.  Effects of acute NEFA manipulation on incretin-induced insulin secretion in participants with and without type 2 diabetes.

Authors:  Brenno Astiarraga; Valéria B Chueire; Aglécio L Souza; Ricardo Pereira-Moreira; Sarah Monte Alegre; Andrea Natali; Andrea Tura; Andrea Mari; Ele Ferrannini; Elza Muscelli
Journal:  Diabetologia       Date:  2018-05-07       Impact factor: 10.122

2.  Baseline Triglyceride Level Affected the Efficacy of Vildagliptin in Treating Type 2 Diabetes: A Post Hoc Analysis of the VISION Study.

Authors:  Lingli Zhou; Xiaoling Cai; Yingying Luo; Fang Zhang; Linong Ji
Journal:  J Diabetes Res       Date:  2019-08-08       Impact factor: 4.011

3.  A Pharmacometabolomic Approach to Predict Response to Metformin in Early-Phase Type 2 Diabetes Mellitus Patients.

Authors:  Jeong-Eun Park; Gui-Hwa Jeong; In-Kyu Lee; Young-Ran Yoon; Kwang-Hyeon Liu; Namyi Gu; Kwang-Hee Shin
Journal:  Molecules       Date:  2018-06-29       Impact factor: 4.411
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.