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Literature DB >> 2721983

Impairment of corneal epithelial barrier function in diabetics.

Abstract

Corneal epithelial permeability was determined using an automatic fluorophotometer in 80 consecutive diabetic patients. The corneal epithelium, which is the most important part of the corneal diffusion barrier, showed a significant increase of permeability to watery, ionic substances (natrium fluorescein). The permeability was increased 5.4 times in comparison with nondiabetic individuals and a distinct correlation of increased permeability with the presence and duration of retinal nonperfusion areas was observed.

Entities: Chemical Disease Species

Mesh：

Substances：
Fluoresceins
Fluorescein

Year: 1989 PMID： 2721983 DOI： 10.1007/BF02169787

Source DB: PubMed Journal: Graefes Arch Clin Exp Ophthalmol ISSN： 0721-832X Impact factor: 3.117

10 in total

1. Mitotic and wound-healing activities of the corneal epithelium; effect of sensory denervation.

Authors: S SIGELMAN; J S FRIEDENWALD
Journal: AMA Arch Ophthalmol Date: 1954-07

2. [Significance of the aqueous humor and marginal loop vessels for the nutrition of the cornea].

Authors: R Turss; H Schebitz
Journal: Ber Zusammenkunft Dtsch Ophthalmol Ges Date: 1972

3. [Nutrition of the cornea having a water impermeable membrane as artificial endothelium].

Authors: M Reim; J Friend; C H Dohlman
Journal: Ber Zusammenkunft Dtsch Ophthalmol Ges Date: 1969

4. Substance P levels in normal and sensorily denervated rabbit eyes.

Authors: J M Butler; D Powell; W G Unger
Journal: Exp Eye Res Date: 1980-03 Impact factor: 3.467

5. Sensory denervation of the rabbit cornea affects epithelial properties.

Authors: R W Beuerman; B Schimmelpfennig
Journal: Exp Neurol Date: 1980-07 Impact factor: 5.330

6. Influence of artificial tears on corneal epithelium in dry-eye syndrome.

Authors: M Göbbels; M Spitznas
Journal: Graefes Arch Clin Exp Ophthalmol Date: 1989 Impact factor: 3.117

7. Neurotrophic corneal ulcers in diabetes mellitus.

Authors: R A Hyndiuk; E L Kazarian; R O Schultz; S Seideman
Journal: Arch Ophthalmol Date: 1977-12

8. Factors related to corneal epithelial complications after closed vitrectomy in diabetics.

Authors: G N Foulks; R A Thoft; H D Perry; F I Tolentino
Journal: Arch Ophthalmol Date: 1979-06

9. Comparison of endothelial cell density in diabetics and a control population.

Authors: G J Pardos; J H Krachmer
Journal: Am J Ophthalmol Date: 1980-08 Impact factor: 5.258

10. Similar epithelial healing rates of the corneas of diabetic and nondiabetic patients.

Authors: R C Snip; R A Thoft; F I Tolentino
Journal: Am J Ophthalmol Date: 1980-10 Impact factor: 5.258

10 in total

22 in total

1. Prevention of diabetic keratopathy.

Authors: Y Kaji
Journal: Br J Ophthalmol Date: 2005-03 Impact factor: 4.638

2. A randomised, placebo controlled clinical trial of the aldose reductase inhibitor CT-112 as management of corneal epithelial disorders in diabetic patients.

Authors: M Nakahara; K Miyata; S Otani; T Miyai; R Nejima; S Yamagami; S Amano
Journal: Br J Ophthalmol Date: 2005-03 Impact factor: 4.638

10. Efficacy of substance P and insulin-like growth factor-1 peptides for preventing postsurgical superficial punctate keratopathy in diabetic patients.

Authors: Nobuhiko Chikamoto; Tai-Ichiro Chikama; Naoyuki Yamada; Teruo Nishida; Tadashi Ishimitsu; Akira Kamiya
Journal: Jpn J Ophthalmol Date: 2009-10-22 Impact factor: 2.447

Impairment of corneal epithelial barrier function in diabetics.

1. Mitotic and wound-healing activities of the corneal epithelium; effect of sensory denervation.

2. [Significance of the aqueous humor and marginal loop vessels for the nutrition of the cornea].

3. [Nutrition of the cornea having a water impermeable membrane as artificial endothelium].

4. Substance P levels in normal and sensorily denervated rabbit eyes.

5. Sensory denervation of the rabbit cornea affects epithelial properties.

6. Influence of artificial tears on corneal epithelium in dry-eye syndrome.

7. Neurotrophic corneal ulcers in diabetes mellitus.

8. Factors related to corneal epithelial complications after closed vitrectomy in diabetics.

9. Comparison of endothelial cell density in diabetics and a control population.

10. Similar epithelial healing rates of the corneas of diabetic and nondiabetic patients.

1. Prevention of diabetic keratopathy.

2. A randomised, placebo controlled clinical trial of the aldose reductase inhibitor CT-112 as management of corneal epithelial disorders in diabetic patients.

Review 3. Optical quality of the diabetic eye: a review.

4. Comparison of Dry Eye Parameters between Diabetics and Non-Diabetics in District of Kuantan, Pahang.

5. Tear secretion and tear film function in insulin dependent diabetics.

6. Unravelling the stromal-nerve interactions in the human diabetic cornea.

7. Comprehensive Review of the Effects of Diabetes on Ocular Health.

8. Description of the sphingolipid content and subspecies in the diabetic cornea.

Review 9. Diabetic keratopathy: Insights and challenges.

10. Efficacy of substance P and insulin-like growth factor-1 peptides for preventing postsurgical superficial punctate keratopathy in diabetic patients.