Literature DB >> 27218241

Hyperpolarization of Nitrogen-15 Schiff Bases by Reversible Exchange Catalysis with para-Hydrogen.

Angus W J Logan1, Thomas Theis2, Johannes F P Colell1, Warren S Warren1,3,4, Steven J Malcolmson5.   

Abstract

NMR with thermal polarization requires relatively concentrated samples, particularly for nuclei with low abundance and low gyromagnetic ratios, such as (15) N. We expand the substrate scope of SABRE, a recently introduced hyperpolarization method, to allow access to (15) N-enriched Schiff bases. These substrates show fractional (15) N polarization levels of up to 2 % while having only minimal (1) H enhancements.
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  NMR spectroscopy; amino acids; homogeneous catalysis; imaging agents; iridium

Year:  2016        PMID： 27218241     DOI： 10.1002/chem.201602393

Source DB:  PubMed          Journal:  Chemistry        ISSN： 0947-6539            Impact factor:   5.236


  17 in total

1.  Spin-Lattice Relaxation of Hyperpolarized Metronidazole in Signal Amplification by Reversible Exchange in Micro-Tesla Fields.

Authors:  Roman V Shchepin; Lamya Jaigirdar; Eduard Y Chekmenev
Journal:  J Phys Chem C Nanomater Interfaces       Date:  2018-02-27       Impact factor: 4.126

2.  Spin Relays Enable Efficient Long-Range Heteronuclear Signal Amplification By Reversible Exchange.

Authors:  Roman V Shchepin; Lamya Jaigirdar; Thomas Theis; Warren S Warren; Boyd M Goodson; Eduard Y Chekmenev
Journal:  J Phys Chem C Nanomater Interfaces       Date:  2017-12-01       Impact factor: 4.126

3.  A versatile synthetic route to the preparation of 15 N heterocycles.

Authors:  Nikita V Chukanov; Bryce E Kidd; Larisa M Kovtunova; Valerii I Bukhtiyarov; Roman V Shchepin; Eduard Y Chekmenev; Boyd M Goodson; Kirill V Kovtunov; Igor V Koptyug
Journal:  J Labelled Comp Radiopharm       Date:  2019-01-07       Impact factor: 1.921

4.  Long-Lived 13C2 Nuclear Spin States Hyperpolarized by Parahydrogen in Reversible Exchange at Microtesla Fields.

Authors:  Zijian Zhou; Jin Yu; Johannes F P Colell; Raul Laasner; Angus Logan; Danila A Barskiy; Roman V Shchepin; Eduard Y Chekmenev; Volker Blum; Warren S Warren; Thomas Theis
Journal:  J Phys Chem Lett       Date:  2017-06-19       Impact factor: 6.475

5.  Delivering strong 1H nuclear hyperpolarization levels and long magnetic lifetimes through signal amplification by reversible exchange.

Authors:  Peter J Rayner; Michael J Burns; Alexandra M Olaru; Philip Norcott; Marianna Fekete; Gary G R Green; Louise A R Highton; Ryan E Mewis; Simon B Duckett
Journal:  Proc Natl Acad Sci U S A       Date:  2017-04-04       Impact factor: 11.205

Review 6.  Parahydrogen-Based Hyperpolarization for Biomedicine.

Authors:  Jan-Bernd Hövener; Andrey N Pravdivtsev; Bryce Kidd; C Russell Bowers; Stefan Glöggler; Kirill V Kovtunov; Markus Plaumann; Rachel Katz-Brull; Kai Buckenmaier; Alexej Jerschow; Francesca Reineri; Thomas Theis; Roman V Shchepin; Shawn Wagner; Pratip Bhattacharya; Niki M Zacharias; Eduard Y Chekmenev
Journal:  Angew Chem Int Ed Engl       Date:  2018-08-01       Impact factor: 15.336

Review 7.  Synthetic Approaches for 15 N-Labeled Hyperpolarized Heterocyclic Molecular Imaging Agents for 15 N NMR Signal Amplification by Reversible Exchange in Microtesla Magnetic Fields.

Authors:  Nikita V Chukanov; Roman V Shchepin; Sameer M Joshi; Mohammad S H Kabir; Oleg G Salnikov; Alexandra Svyatova; Igor V Koptyug; Juri G Gelovani; Eduard Y Chekmenev
Journal:  Chemistry       Date:  2021-05-21       Impact factor: 5.020

8.  Open-Source Automated Parahydrogen Hyperpolarizer for Molecular Imaging Using (13)C Metabolic Contrast Agents.

Authors:  Aaron M Coffey; Roman V Shchepin; Milton L Truong; Ken Wilkens; Wellington Pham; Eduard Y Chekmenev
Journal:  Anal Chem       Date:  2016-08-01       Impact factor: 6.986

9.  Iridium Cyclooctene Complex That Forms a Hyperpolarization Transfer Catalyst before Converting to a Binuclear C-H Bond Activation Product Responsible for Hydrogen Isotope Exchange.

Authors:  Wissam Iali; Gary G R Green; Sam J Hart; Adrian C Whitwood; Simon B Duckett
Journal:  Inorg Chem       Date:  2016-11-09       Impact factor: 5.165

10.  Using signal amplification by reversible exchange (SABRE) to hyperpolarise 119Sn and 29Si NMR nuclei.

Authors:  Alexandra M Olaru; Alister Burt; Peter J Rayner; Sam J Hart; Adrian C Whitwood; Gary G R Green; Simon B Duckett
Journal:  Chem Commun (Camb)       Date:  2016-12-13       Impact factor: 6.222
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