Literature DB >> 2721667

Immunological evidence for the role of phosphoprotein p68/pI = 7.3 in premessenger RNA splicing.

C C Liew1, H C Smith.   

Abstract

A 68 kDa (pI = 7.3) nuclear phosphoprotein has been previously characterized as a component of transcriptionally active chromatin. Two-dimensional PAGE Western blotting and radioimmunoassay with monoclonal antibodies have identified this protein in nuclear extracts used for in vitro RNA splicing. In vitro splicing activity could be quantitatively inhibited by preincubating nuclear extracts with the antibodies, but the assembly of 60 S spliceosomes could not.

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Year:  1989        PMID： 2721667     DOI： 10.1016/0014-5793(89)80440-5

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  4 in total

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Authors:  D B Cowan; G Chaban; C C Liew
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Journal:  J Virol       Date:  2007-01-31       Impact factor: 5.103

3.  Characterization of Zn(2+)-binding nuclear proteins present in the myocardium.

Authors:  C C Liew; E Cukerman
Journal:  Mol Cell Biochem       Date:  1993-04-21       Impact factor: 3.396

4.  Nuclear ARVCF protein binds splicing factors and contributes to the regulation of alternative splicing.

Authors:  Ulrike Rappe; Tanja Schlechter; Moritz Aschoff; Agnes Hotz-Wagenblatt; Ilse Hofmann
Journal:  J Biol Chem       Date:  2014-03-18       Impact factor: 5.157
  4 in total

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