Eric Chung1, David Ralph2, Ates Kagioglu3, Guilio Garaffa2, Ahmed Shamsodini4, Trinity Bivalacqua5, Sidney Glina6, Lawrence Hakim7, Hossein Sadeghi-Nejad8, Gregory Broderick9. 1. Department of Urology, University of Queensland, Princess Alexandra Hospital, Brisbane, QLD, Australia; AndroUrology Centre, St. Andrew's War Memorial Hospital, Brisbane, QLD, Australia. Electronic address: ericchg@hotmail.com. 2. Institute of Urology, University College London Hospital, London, UK. 3. Department of Urology, Istanbul Faculty of Medicine, Istanbul, Turkey. 4. Urology Department, Hamad General Hospital, Doha, Qatar. 5. James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins School of Medicine, Baltimore, MD, USA. 6. Instituto H. Ellis and Department of Urology, Ipiranga Hospital, Sao Paulo, Brazil. 7. Department of Urology, Cleveland Clinic Florida, Weston, FL, USA. 8. Division of Urology, UMDNJ-Robert Wood Johnson Medical School, Newark, NJ, USA. 9. Department of Urology, Mayo Clinic, Jacksonville, FL, USA.
Abstract
INTRODUCTION: Despite recent advances in our knowledge and treatment strategies in Peyronie's Disease (PD), much remained unknown about this disease. AIM: To provide a clinical framework and key guideline statements to assist clinicians in an evidence-based management of PD. METHODS: A systematic literature search was conducted to identify published literature relevant to PD. The search included all relevant articles published up to June 2015, including preclinical studies and published guidelines. References used in the text were assessed according to their level of evidence, and guideline recommendations were graded based on the Oxford Centre for Evidence-Based Medicine Levels of Evidence. Owing to the paucity of larger series and randomized placebo-controlled trials with regard to surgical intervention, guideline statements are provided as clinical principle or expert opinion. MAIN OUTCOME MEASURES: This literature was discussed at a panel meeting, and selected articles with the highest evidence available were used to create consensus guideline statements for the Fourth International Consultation on Sexual Medicine guidelines on PD. RESULTS: In addition to existing Third International Consultation on Sexual Medicine guidelines on PD, seven new summary recommendations were created. CONCLUSION: A greater understanding of the scientific basis of PD is greatly needed to address our understanding of the pathophysiology, clinical epidemiology, psychosocial, and diagnostic assessment as well as treatment strategies.
INTRODUCTION: Despite recent advances in our knowledge and treatment strategies in Peyronie's Disease (PD), much remained unknown about this disease. AIM: To provide a clinical framework and key guideline statements to assist clinicians in an evidence-based management of PD. METHODS: A systematic literature search was conducted to identify published literature relevant to PD. The search included all relevant articles published up to June 2015, including preclinical studies and published guidelines. References used in the text were assessed according to their level of evidence, and guideline recommendations were graded based on the Oxford Centre for Evidence-Based Medicine Levels of Evidence. Owing to the paucity of larger series and randomized placebo-controlled trials with regard to surgical intervention, guideline statements are provided as clinical principle or expert opinion. MAIN OUTCOME MEASURES: This literature was discussed at a panel meeting, and selected articles with the highest evidence available were used to create consensus guideline statements for the Fourth International Consultation on Sexual Medicine guidelines on PD. RESULTS: In addition to existing Third International Consultation on Sexual Medicine guidelines on PD, seven new summary recommendations were created. CONCLUSION: A greater understanding of the scientific basis of PD is greatly needed to address our understanding of the pathophysiology, clinical epidemiology, psychosocial, and diagnostic assessment as well as treatment strategies.
Authors: Anthony J Bella; Jay C Lee; Ethan D Grober; Serge Carrier; Francois Benard; Gerald B Brock Journal: Can Urol Assoc J Date: 2018-02-22 Impact factor: 1.862
Authors: Edoardo Pozzi; Paolo Capogrosso; Luca Boeri; Walter Cazzaniga; Rayan Matloob; Eugenio Ventimiglia; Davide Oreggia; Nicolò Schifano; Luigi Candela; Costantino Abbate; Francesco Montorsi; Andrea Salonia Journal: Int J Impot Res Date: 2020-07-01 Impact factor: 2.896
Authors: Eric Chung; Carlo Bettocchi; Paulo Egydio; Chris Love; Daniar Osmonov; Sean Park; David Ralph; Zhong Cheng Xin; Gerald Brock Journal: Nat Rev Urol Date: 2022-06-16 Impact factor: 16.430
Authors: Madeleine G Manka; Lindsay A White; Faysal A Yafi; John P Mulhall; Laurence A Levine; Matthew J Ziegelmann Journal: J Sex Med Date: 2021-01-07 Impact factor: 3.802
Authors: Ateş Kadıoğlu; Emre Salabaş; Abdulkadir Özmez; Abdullah Feyyaz Ural; Ömer Barış Yücel; Mazhar Ortaç; Yaşar Pazır; Bahadır Ermeç Journal: Turk J Urol Date: 2017-01-01