Literature DB >> 27215676

Base-catalyzed controllable reaction of 3-ylideneoxindoles with O-Boc hydroxycarbamates for the synthesis of amidoacrylates and spiroaziridine oxindoles.

Yi-Yin Liu1, Shu-Wen Duan, Rui Zhang, Yun-Hang Liu, Jia-Rong Chen, Wen-Jing Xiao.   

Abstract

A base-catalyzed divergent reaction of 3-ylideneoxindoles with O-Boc hydroxycarbamates has been developed to provide efficient access to various amidoacrylates and spiroaziridine oxindoles with generally high yields, which should be potentially useful in drug discovery.

Entities:  

Year:  2016        PMID: 27215676     DOI: 10.1039/c6ob00891g

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  2 in total

1.  Molecular Hybridization-Guided One-Pot Multicomponent Synthesis of Turmerone Motif-Fused 3,3'-Pyrrolidinyl-dispirooxindoles via a 1,3-Dipolar Cycloaddition Reaction.

Authors:  Bing Lin; Gen Zhou; Yi Gong; Qi-Di Wei; Min-Yi Tian; Xiong-Li Liu; Ting-Ting Feng; Ying Zhou; Wei-Cheng Yuan
Journal:  Molecules       Date:  2017-04-17       Impact factor: 4.411

2.  Synthesis of (Z)-3-[amino(phenyl)methylidene]-1,3-dihydro-2H-indol-2-ones using an Eschenmoser coupling reaction.

Authors:  Lukáš Marek; Lukáš Kolman; Jiří Váňa; Jan Svoboda; Jiří Hanusek
Journal:  Beilstein J Org Chem       Date:  2021-02-23       Impact factor: 2.883

  2 in total

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