Literature DB >> 27213295

Protease-activated receptor 4 is more important than protease-activated receptor 1 for the thrombin-induced procoagulant effect on platelets.

T L Lindahl1,2, A S Macwan1, S Ramström1.   

Abstract

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Year:  2016        PMID： 27213295     DOI： 10.1111/jth.13374

Source DB:  PubMed          Journal:  J Thromb Haemost        ISSN： 1538-7836            Impact factor:   5.824


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  4 in total

1.  Development of a Series of (1-Benzyl-3-(6-methoxypyrimidin-3-yl)-5-(trifluoromethoxy)-1H-indol-2-yl)methanols as Selective Protease Activated Receptor 4 (PAR4) Antagonists with in Vivo Utility and Activity Against γ-Thrombin.

Authors:  Kayla J Temple; Matthew T Duvernay; Summer E Young; Wandong Wen; Wenjun Wu; Jae G Maeng; Anna L Blobaum; Shaun R Stauffer; Heidi E Hamm; Craig W Lindsley
Journal:  J Med Chem       Date:  2016-08-08       Impact factor: 7.446

2.  Discovery and Optimization of a Novel Series of Competitive and Central Nervous System-Penetrant Protease-Activated Receptor 4 (PAR4) Inhibitors.

Authors:  Jeanette L Bertron; Matthew T Duvernay; Sidnee G Mitchell; Shannon T Smith; Jae G Maeng; Anna L Blobaum; Dexter C Davis; Jens Meiler; Heidi E Hamm; Craig W Lindsley
Journal:  ACS Chem Neurosci       Date:  2021-12-02       Impact factor: 4.418

3.  Supramaximal calcium signaling triggers procoagulant platelet formation.

Authors:  Nima Abbasian; Sarah L Millington-Burgess; Shirom Chabra; Jean-Daniel Malcor; Matthew T Harper
Journal:  Blood Adv       Date:  2020-01-14

Review 4.  Platelets Contribution to Thrombin Generation in Philadelphia-Negative Myeloproliferative Neoplasms: The "Circulating Wound" Model.

Authors:  Alessandro Lucchesi; Roberta Napolitano; Maria Teresa Bochicchio; Giulio Giordano; Mariasanta Napolitano
Journal:  Int J Mol Sci       Date:  2021-10-20       Impact factor: 5.923
  4 in total

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