Literature DB >> 27212260

Shedding light on betL*: pPL2-lux mediated real-time analysis of betL* expression in Listeria monocytogenes.

Shauna M Keane1, Eamonn P Culligan1, Roland F Hoffmann2, Cormac G M Gahan2,3,4, Colin Hill2,3, William J Snelling5, Roy D Sleator1,2.   

Abstract

We propose a mechanism of action for the betL* mutation which is based on DNA topology. Removing a single thymine residue from the betL σ(A) promoter's -10 and -35 spacer results in a 'twist'-mediated activation of transcription which accounts for the osmotolerance phenotype observed for strains expressing betL*.

Entities:  

Keywords:  Listeria; betL*; lux; osmotolerance

Mesh：

Substances：

Year:  2016        PMID： 27212260      PMCID： PMC4879987          DOI： 10.1080/21655979.2016.1171438

Source DB:  PubMed          Journal:  Bioengineered        ISSN： 2165-5979            Impact factor:   3.269


  25 in total

Review 1.  Bacterial osmoadaptation: the role of osmolytes in bacterial stress and virulence.

Authors:  Roy D Sleator; Colin Hill
Journal:  FEMS Microbiol Rev       Date:  2002-03       Impact factor: 16.408

2.  Identification and disruption of BetL, a secondary glycine betaine transport system linked to the salt tolerance of Listeria monocytogenes LO28.

Authors:  R D Sleator; C G Gahan; T Abee; C Hill
Journal:  Appl Environ Microbiol       Date:  1999-05       Impact factor: 4.792

3.  Compatible solutes: A listerial passe-partout?

Authors:  Roy D Sleator; Colin Hill
Journal:  Gut Microbes       Date:  2009-12-17

4.  A physiological role for DNA supercoiling in the osmotic regulation of gene expression in S. typhimurium and E. coli.

Authors:  C F Higgins; C J Dorman; D A Stirling; L Waddell; I R Booth; G May; E Bremer
Journal:  Cell       Date:  1988-02-26       Impact factor: 41.582

5.  agr expression precedes escape of internalized Staphylococcus aureus from the host endosome.

Authors:  S N Qazi; E Counil; J Morrissey; C E Rees; A Cockayne; K Winzer; W C Chan; P Williams; P J Hill
Journal:  Infect Immun       Date:  2001-11       Impact factor: 3.441

6.  Novel luciferase reporter system for in vitro and organ-specific monitoring of differential gene expression in Listeria monocytogenes.

Authors:  Peter A Bron; Ian R Monk; Sinéad C Corr; Colin Hill; Cormac G M Gahan
Journal:  Appl Environ Microbiol       Date:  2006-04       Impact factor: 4.792

7.  Construction, characterization, and use of two Listeria monocytogenes site-specific phage integration vectors.

Authors:  Peter Lauer; Man Yin Nora Chow; Martin J Loessner; Daniel A Portnoy; Richard Calendar
Journal:  J Bacteriol       Date:  2002-08       Impact factor: 3.490

8.  Improving gastric transit, gastrointestinal persistence and therapeutic efficacy of the probiotic strain Bifidobacterium breve UCC2003.

Authors:  Vivien M Sheehan; Roy D Sleator; Colin Hill; Gerald F Fitzgerald
Journal:  Microbiology       Date:  2007-10       Impact factor: 2.777

9.  Compatible solutes: the key to Listeria's success as a versatile gastrointestinal pathogen?

Authors:  Roy D Sleator; Colin Hill
Journal:  Gut Pathog       Date:  2010-12-10       Impact factor: 4.181

10.  DNA twist, flexibility and transcription of the osmoregulated proU promoter of Salmonella typhimurium.

Authors:  B J Jordi; T A Owen-Hughes; C S Hulton; C F Higgins
Journal:  EMBO J       Date:  1995-11-15       Impact factor: 11.598
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