Literature DB >> 27211664

Antibacterial and antifungal activities of thymol: A brief review of the literature.

Anna Marchese1, Ilkay Erdogan Orhan2, Maria Daglia3, Ramona Barbieri1, Arianna Di Lorenzo3, Seyed Fazel Nabavi4, Olga Gortzi5, Morteza Izadi6, Seyed Mohammad Nabavi7.   

Abstract

Thymol (2-isopropyl-5-methylphenol) is the main monoterpene phenol occurring in essential oils isolated from plants belonging to the Lamiaceae family (Thymus, Ocimum, Origanum, and Monarda genera), and other plants such as those belonging to the Verbenaceae, Scrophulariaceae, Ranunculaceae, and Apiaceae families. These essential oils are used in the food industry for their flavouring and preservative properties, in commercial mosquito repellent formulations for their natural repellent effect, in aromatherapy, and in traditional medicine for the treatment of headaches, coughs, and diarrhea. Many different activities of thymol such as antioxidant, anti-inflammatory, local anaesthetic, antinociceptive, cicatrizing, antiseptic, and especially antibacterial and antifungal properties have been shown. This review aims to critically evaluate the available literature regarding the antibacterial and antifungal effects of thymol.
Copyright © 2016 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Antibacterial; Antifungal; Monoterpene; Thymol; Thymus

Mesh:

Substances:

Year:  2016        PMID: 27211664     DOI: 10.1016/j.foodchem.2016.04.111

Source DB:  PubMed          Journal:  Food Chem        ISSN: 0308-8146            Impact factor:   7.514


  91 in total

1.  Thymus vulgaris L. and thymol assist murine macrophages (RAW 264.7) in the control of in vitro infections by Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans.

Authors:  Jonatas Rafael de Oliveira; Leandro Wagner Figueira; Fábia Lugli Sper; Vanessa Marques Meccatti; Samira Esteves Afonso Camargo; Luciane Dias de Oliveira
Journal:  Immunol Res       Date:  2017-08       Impact factor: 2.829

2.  Development and Characterization of Monoolein-Based Liposomes of Carvacrol, Cinnamaldehyde, Citral, or Thymol with Anti-Candida Activities.

Authors:  Katherine Miranda-Cadena; Marisol Dias; Augusto Costa-Barbosa; Tony Collins; Cristina Marcos-Arias; Elena Eraso; Célia Pais; Guillermo Quindós; Paula Sampaio
Journal:  Antimicrob Agents Chemother       Date:  2021-03-18       Impact factor: 5.191

3.  Chemical composition and bioactivity of essential oils from flower and fruit of Thymbra capitata and Thymus species.

Authors:  Jonathan Delgado-Adámez; María Garrido; Maria Elena Bote; María C Fuentes-Pérez; Javier Espino; Daniel Martín-Vertedor
Journal:  J Food Sci Technol       Date:  2017-04-10       Impact factor: 2.701

4.  Ocimum basilicum but not Ocimum gratissimum present cytotoxic effects on human breast cancer cell line MCF-7, inducing apoptosis and triggering mTOR/Akt/p70S6K pathway.

Authors:  Renan Gianoti Torres; Livia Casanova; Julia Carvalho; Mariah Celestino Marcondes; Sonia Soares Costa; Mauro Sola-Penna; Patricia Zancan
Journal:  J Bioenerg Biomembr       Date:  2018-03-28       Impact factor: 2.945

Review 5.  Ethnobotany and the Role of Plant Natural Products in Antibiotic Drug Discovery.

Authors:  Gina Porras; François Chassagne; James T Lyles; Lewis Marquez; Micah Dettweiler; Akram M Salam; Tharanga Samarakoon; Sarah Shabih; Darya Raschid Farrokhi; Cassandra L Quave
Journal:  Chem Rev       Date:  2020-11-09       Impact factor: 60.622

6.  Drying Effects on Chemical Composition and Antioxidant Activity of Lippia thymoides Essential Oil, a Natural Source of Thymol.

Authors:  Lidiane Diniz do Nascimento; Sebastião Gomes Silva; Márcia Moraes Cascaes; Kauê Santana da Costa; Pablo Luis Baia Figueiredo; Cristiane Maria Leal Costa; Eloisa Helena de Aguiar Andrade; Lênio José Guerreiro de Faria
Journal:  Molecules       Date:  2021-04-30       Impact factor: 4.411

7.  Antibacterial Activities of Homemade Matrices Miming Essential Oils Compared to Commercial Ones.

Authors:  Sofia Oliveira Ribeiro; Véronique Fontaine; Véronique Mathieu; Zhiri Abdesselam; Baudoux Dominique; Stévigny Caroline; Souard Florence
Journal:  Antibiotics (Basel)       Date:  2021-05-14

8.  Enhancement of the Antioxidant and Antimicrobial Activities of Porphyran through Chemical Modification with Tyrosine Derivatives.

Authors:  Pedro Adão; João Reboleira; Marco Teles; Beatriz Santos; Nádia Ribeiro; Carlos M Teixeira; Mafalda Guedes; João Costa Pessoa; Susana Bernardino
Journal:  Molecules       Date:  2021-05-14       Impact factor: 4.411

9.  In silico molecular docking and in vitro antimicrobial efficacy of phytochemicals against multi-drug-resistant enteroaggregative Escherichia coli and non-typhoidal Salmonella spp.

Authors:  Padikkamannil Abishad; Pollumahanti Niveditha; Varsha Unni; Jess Vergis; Nitin Vasantrao Kurkure; Sandeep Chaudhari; Deepak Bhiwa Rawool; Sukhadeo Baliram Barbuddhe
Journal:  Gut Pathog       Date:  2021-07-17       Impact factor: 4.181

10.  A Regioselective Synthesis of Novel Functionalized Organochalcogen Compounds by Chalcogenocyclofunctionalization Reactions Based on Chalcogen Halides and Natural Products.

Authors:  Maxim V Musalov; Vladimir A Potapov; Vladimir A Yakimov; Maria V Musalova; Arkady A Maylyan; Sergey V Zinchenko; Svetlana V Amosova
Journal:  Molecules       Date:  2021-06-18       Impact factor: 4.411

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