Literature DB >> 27210022

Does topical use of autologous serum help to reduce post-tonsillectomy morbidity? A prospective, controlled preliminary study.

M Kara1, H Erdoğan1, H B Altinişik2, H Aylanç3, O Güçlü1, F S Dereköy1.   

Abstract

BACKGROUND: To evaluate the effects of autologous serum usage on throat pain, haemorrhage and tonsillar fossa epithelisation in patients after tonsillectomy.
METHODS: Thirty-two patients (aged 4-15 years) were included in the study. Tonsillectomy was performed and autologous serum was administered topically to the right tonsillar fossa during the operation, and at 8 and 24 hours post-operatively. The left side served as the control. A visual analogue scale was used to record the patient's pain every day. Each patient's oropharynx was observed on the 5th and 10th post-operative days to examine bleeding and epithelisation.
RESULTS: The pain scores for the side administered autologous serum were significantly lower than those for the control side, on the night following the operation and on the 1st, 2nd, 5th and 6th post-operative days. Tonsillar fossa epithelisation was significantly accelerated on the study side compared with the control side on the 5th and 10th post-operative days.
CONCLUSION: In tonsillectomy patients, topically administered autologous serum contributed to throat pain relief and tonsillar fossa epithelisation during the post-operative period.

Entities:  

Keywords:  Hemorrhage; Postoperative Pain; Serum; Tonsillectomy; Wound Healing

Mesh:

Year:  2016        PMID: 27210022     DOI: 10.1017/S0022215116007970

Source DB:  PubMed          Journal:  J Laryngol Otol        ISSN: 0022-2151            Impact factor:   1.469


  4 in total

1.  The effect of applying amniotic membrane on post-tonsillectomy pain and bleeding.

Authors:  Mohammad Faramarzi; Mahmood Shishegar; Tayebeh Kazemi; Hamid Tavakolpour Saleh; Sareh Roosta
Journal:  Eur Arch Otorhinolaryngol       Date:  2020-06-29       Impact factor: 2.503

2.  Beneficial effects of dexmedetomidine on early postoperative cognitive dysfunction in pediatric patients with tonsillectomy.

Authors:  Chuanlai Han; Rong Fu; Weifu Lei
Journal:  Exp Ther Med       Date:  2018-05-17       Impact factor: 2.447

3.  Is Ginger Effective in Reducing Post-tonsillectomy Morbidity? A Prospective Randomised Clinical Trial.

Authors:  İlker Koçak; Cemil Yücepur; Ozan Gökler
Journal:  Clin Exp Otorhinolaryngol       Date:  2017-09-08       Impact factor: 3.372

Review 4.  Topical biomaterials to prevent post-tonsillectomy hemorrhage.

Authors:  Lumei Liu; Cole Rodman; Noah E Worobetz; Jed Johnson; Charles Elmaraghy; Tendy Chiang
Journal:  J Otolaryngol Head Neck Surg       Date:  2019-09-06
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.