Literature DB >> 27209407

Scientific Achievements May Not Reach Everyone: Understanding Disparities in Acute Leukemia.

Manali I Patel1.   

Abstract

Over the past decade, scientific advancements have resulted in improved survival from acute leukemia. Continued advancements are expected given the attention to precision medicine and the resulting growth in development and adoption of risk-stratified, personalized therapies. While precision medicine has great potential to improve acute leukemia outcomes, there remain significant barriers to ensuring equitable access to these technologies and receipt of these prescribed targeted, personalized therapies. Over the past 3 years, studies report persistent outcome disparities among patients from specific racial and ethnic backgrounds, insurance and socioeconomic status, and other socio-demographic factors after a diagnosis of acute leukemia. A few recent studies examine etiologies for acute leukemia disparities and highlight the importance of ensuring access and equitable delivery of scientific advancements. In the context of continued scientific progress, future strategies require thoughtfully considered improvements in the delivery of care that can overcome the current challenges our patients face.

Entities:  

Keywords:  Acute leukemia; Disparities; Precision medicine; Survival

Mesh:

Year:  2016        PMID: 27209407     DOI: 10.1007/s11899-016-0329-y

Source DB:  PubMed          Journal:  Curr Hematol Malig Rep        ISSN: 1558-8211            Impact factor:   3.952


  40 in total

1.  Economic analysis of targeting chemotherapy using a 21-gene RT-PCR assay in lymph-node-negative, estrogen-receptor-positive, early-stage breast cancer.

Authors:  John Hornberger; Leon E Cosler; Gary H Lyman
Journal:  Am J Manag Care       Date:  2005-05       Impact factor: 2.229

2.  Chimeric antigen receptor T cells for sustained remissions in leukemia.

Authors:  Shannon L Maude; Noelle Frey; Pamela A Shaw; Richard Aplenc; David M Barrett; Nancy J Bunin; Anne Chew; Vanessa E Gonzalez; Zhaohui Zheng; Simon F Lacey; Yolanda D Mahnke; Jan J Melenhorst; Susan R Rheingold; Angela Shen; David T Teachey; Bruce L Levine; Carl H June; David L Porter; Stephan A Grupp
Journal:  N Engl J Med       Date:  2014-10-16       Impact factor: 91.245

3.  Understanding disparities in leukemia: a national study.

Authors:  M I Patel; Y Ma; B S Mitchell; K F Rhoads
Journal:  Cancer Causes Control       Date:  2012-09-13       Impact factor: 2.506

4.  Age and acute myeloid leukemia.

Authors:  Frederick R Appelbaum; Holly Gundacker; David R Head; Marilyn L Slovak; Cheryl L Willman; John E Godwin; Jeanne E Anderson; Stephen H Petersdorf
Journal:  Blood       Date:  2006-02-02       Impact factor: 22.113

5.  Proposed classification of lymphoid neoplasms for epidemiologic research from the Pathology Working Group of the International Lymphoma Epidemiology Consortium (InterLymph).

Authors:  Lindsay M Morton; Jennifer J Turner; James R Cerhan; Martha S Linet; Patrick A Treseler; Christina A Clarke; Andrew Jack; Wendy Cozen; Marc Maynadié; John J Spinelli; Adele Seniori Costantini; Thomas Rüdiger; Aldo Scarpa; Tongzhang Zheng; Dennis D Weisenburger
Journal:  Blood       Date:  2007-03-27       Impact factor: 22.113

6.  Treatment outcomes in black and white children with cancer: results from the SEER database and St Jude Children's Research Hospital, 1992 through 2007.

Authors:  Ching-Hon Pui; Deqing Pei; Alberto S Pappo; Scott C Howard; Cheng Cheng; John T Sandlund; Wayne L Furman; Raul C Ribeiro; Sheri L Spunt; Jeffrey E Rubnitz; Sima Jeha; Melissa M Hudson; Larry E Kun; Thomas E Merchant; Mehmet Kocak; Alberto Broniscer; Monika L Metzger; James R Downing; Wing Leung; William E Evans; Amar Gajjar
Journal:  J Clin Oncol       Date:  2012-04-30       Impact factor: 44.544

7.  Chimeric antigen receptor-modified T cells for acute lymphoid leukemia.

Authors:  Stephan A Grupp; Michael Kalos; David Barrett; Richard Aplenc; David L Porter; Susan R Rheingold; David T Teachey; Anne Chew; Bernd Hauck; J Fraser Wright; Michael C Milone; Bruce L Levine; Carl H June
Journal:  N Engl J Med       Date:  2013-03-25       Impact factor: 91.245

8.  Age and genetics: how do prognostic factors at diagnosis explain disparities in acute myeloid leukemia?

Authors:  Manali I Patel; Yifei Ma; Beverly S Mitchell; Kim F Rhoads
Journal:  Am J Clin Oncol       Date:  2015-04       Impact factor: 2.339

9.  Nonadherence to oral mercaptopurine and risk of relapse in Hispanic and non-Hispanic white children with acute lymphoblastic leukemia: a report from the children's oncology group.

Authors:  Smita Bhatia; Wendy Landier; Muyun Shangguan; Lindsey Hageman; Alexandra N Schaible; Andrea R Carter; Cara L Hanby; Wendy Leisenring; Yutaka Yasui; Nancy M Kornegay; Leo Mascarenhas; A Kim Ritchey; Jacqueline N Casillas; David S Dickens; Jane Meza; William L Carroll; Mary V Relling; F Lennie Wong
Journal:  J Clin Oncol       Date:  2012-05-07       Impact factor: 44.544

10.  Disparities in early death and survival in children, adolescents, and young adults with acute promyelocytic leukemia in California.

Authors:  Renata Abrahão; Raul C Ribeiro; Bruno C Medeiros; Ruth H Keogh; Theresa H M Keegan
Journal:  Cancer       Date:  2015-08-11       Impact factor: 6.921

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  1 in total

1.  Navigating Access to Cancer Care: Identifying Barriers to Precision Cancer Medicine.

Authors:  Kayla E Cooper; Khadijah E Abdallah; Rebekah S M Angove; Kathleen D Gallagher; Vence L Bonham
Journal:  Ethn Dis       Date:  2022-01-20       Impact factor: 2.006

  1 in total

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