Literature DB >> 27207599

Predictors of urethral stricture recurrence after endoscopic urethrotomy.

L Redón-Gálvez1, R Molina-Escudero2, M Álvarez-Ardura2, H Otaola-Arca2, R O Alarcón Parra2, Á Páez-Borda2.   

Abstract

OBJECTIVE: The aim of the study was to analyse the clinical-demographic variables of the series and the predictors of urethral stricture recurrence after endoscopic urethrotomy.
MATERIAL AND METHODS: We retrospectively analysed 67 patients who underwent Sachse endoscopic urethrotomy between June 2006 and September 2014. Those patients who had previously undergone endoscopic urethrotomy or urethroplasty were excluded. The other patients who presented urethral stricture were included. We analysed age, weight, smoking habit, and cardiovascular risk factors, as well as the number, location, length and aetiology of the strictures, previous urethrotomies, vesical catheter duration and postsurgical dilatations. A univariate and multivariate analysis was conducted using the chi-squared test or Fisher's test and logistic regression to identify the variables related to recurrence.
RESULTS: Thirty-seven percent of the patients had a relapse. The majority of the patients were older than 60 years (56.7%), obese (74.6%), nonsmokers (88%) and had no cardiovascular factors (56.7%). The majority of the strictures were single (94%), <1cm (82%), bulbar urethral (64.2%), iatrogenic (67.2%) and with no prior urethrotomy (89.6%). The majority of the patients carried a vesical catheter for <15 days (85.1%) and did not undergo postsurgical dilatation (65.7%). Only the length of the stricture was an independent risk factor for recurrence (P=.025; relative risk, 5.7; 95% CI 1.21-26.41).
CONCLUSIONS: In the treatment of urethral strictures through endoscopic urethrotomy, a stricture length >1cm is the only factor that predicts an increase in the risk of recurrence. We found no clinical or demographic factors that caused an increase in the incidence of recurrence. Similarly, technical factors such as increasing the bladder catheterisation time and urethral dilatations did not change the course of the disease. Their routine use is therefore unnecessary.
Copyright © 2016 AEU. Publicado por Elsevier España, S.L.U. All rights reserved.

Entities:  

Keywords:  Endoscopic urethrotomy; Estenosis uretral; Recidiva; Recurrence; Urethral stricture; Uretrotomía endoscópica

Mesh:

Year:  2016        PMID: 27207599     DOI: 10.1016/j.acuro.2016.03.013

Source DB:  PubMed          Journal:  Actas Urol Esp        ISSN: 0210-4806            Impact factor:   0.994


  3 in total

1.  Establishment of the U.L.T.R.A. measurement rating system for anterior urethral stricture.

Authors:  Lei Chen; Rui Hou; Chao Feng; Xinru Zhang; Diancheng Li; Jie Chen; Bing Hu
Journal:  Int Urol Nephrol       Date:  2017-05-02       Impact factor: 2.370

2.  Canadian Urological Association guideline on male urethral stricture.

Authors:  Keith F Rourke; Blayne Welk; Ron Kodama; Greg Bailly; Tim Davies; Nancy Santesso; Philippe D Violette
Journal:  Can Urol Assoc J       Date:  2020-10       Impact factor: 2.052

Review 3.  Tissue Engineering of the Urethra: From Bench to Bedside.

Authors:  Dusan Pastorek; Martina Culenova; Maria Csobonyeiova; Veronika Skuciova; Lubos Danisovic; Stanislav Ziaran
Journal:  Biomedicines       Date:  2021-12-15
  3 in total

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