Literature DB >> 27207415

Novel aspects of platelet factor XIII function.

Joanne L Mitchell1, Nicola J Mutch2.   

Abstract

Pools of factor XIII (FXIII) exist in the plasma and within the cytoplasm of hematopoietic cells, including platelets. The functions of the cellular form, FXIII-A, have been assumed to be intracellular in nature, as the protein lacks a signal sequence for its release. Mounting evidence now suggests that platelet FXIII-A modulates hemostasis by several different mechanisms. In this condensed review we discuss recent advances in our understanding of the novel intracellular and extracellular functions of platelet FXIII-A.
Copyright © 2016 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  factor XIII; fibrin; fibrinolysis; platelets; α(2)-antiplasmin

Mesh：

Substances：

Year:  2016        PMID： 27207415     DOI： 10.1016/S0049-3848(16)30356-5

Source DB:  PubMed          Journal:  Thromb Res        ISSN： 0049-3848            Impact factor:   3.944


  7 in total

Review 1.  Fibrinogen and Factor XIII in Venous Thrombosis and Thrombus Stability.

Authors:  Alisa S Wolberg; Yaqiu Sang
Journal:  Arterioscler Thromb Vasc Biol       Date:  2022-06-02       Impact factor: 10.514

2.  Factor XIII is a newly identified binding partner for platelet collagen receptor GPVI-dimer-An interaction that may modulate fibrin crosslinking.

Authors:  Masaaki Moroi; Isuru Induruwa; Richard W Farndale; Stephanie M Jung
Journal:  Res Pract Thromb Haemost       Date:  2022-04-24

3.  The Effect of Activated FXIII, a Transglutaminase, on Vascular Smooth Muscle Cells.

Authors:  Réka Bogáti; Éva Katona; Amir H Shemirani; Enikő Balogh; Helga Bárdos; Viktória Jeney; László Muszbek
Journal:  Int J Mol Sci       Date:  2022-05-23       Impact factor: 6.208

4.  Development and validation of a high throughput whole blood thrombolysis plate assay.

Authors:  T Bonnard; L S Law; Z Tennant; C E Hagemeyer
Journal:  Sci Rep       Date:  2017-05-24       Impact factor: 4.379

5.  Activation mechanism dependent surface exposure of cellular factor XIII on activated platelets and platelet microparticles.

Authors:  Laura Somodi; Ildikó Beke Debreceni; Gréta Kis; Marco Cozzolino; János Kappelmayer; Miklós Antal; György Panyi; Helga Bárdos; Nicola J Mutch; László Muszbek
Journal:  J Thromb Haemost       Date:  2022-02-21       Impact factor: 16.036

Review 6.  Factor XIII Subunit A in the Skin: Applications in Diagnosis and Treatment.

Authors:  Lilla Paragh; Daniel Törőcsik
Journal:  Biomed Res Int       Date:  2017-08-15       Impact factor: 3.411

7.  Structure functional insights into calcium binding during the activation of coagulation factor XIII A.

Authors:  Sneha Singh; Johannes Dodt; Peter Volkers; Emma Hethershaw; Helen Philippou; Vytautus Ivaskevicius; Diana Imhof; Johannes Oldenburg; Arijit Biswas
Journal:  Sci Rep       Date:  2019-08-05       Impact factor: 4.379
  7 in total

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