Literature DB >> 27207269

Robot-assisted partial cystectomy: perioperative outcomes and early oncological efficacy.

David M Golombos1, Padraic O'Malley1, Patrick Lewicki1, Benjamin V Stone1, Douglas S Scherr1.   

Abstract

OBJECTIVE: To report on patients undergoing robot-assisted partial cystectomy (RAPC), focusing on perioperative outcomes over a range of clinical, anatomical and pathological variables, as well as the overall oncological efficacy of this approach. PATIENTS AND METHODS: We retrospectively reviewed all patients who underwent RAPC by a single surgeon between 2005 and 2015. We identified 29 patients who underwent surgery for definitive management of a primary bladder tumour. Clinicopathological data and perioperative variables were recorded. Continuous variables were compared using the Student's t-test. Prediction of perioperative outcomes for those undergoing RAPC for intra-diverticular neoplasms was done using univariate logistic regression. Survival was estimated using the Kaplan-Meier method.
RESULTS: The median (interquartile range) patient age was 75 (65-81) years, 18 patients (62.1%) had an American Society of Anesthesiologists classification of ≥3, and 10 patients (34.5%) had a history of prior abdominal surgery. The median estimated blood loss (EBL) was 50 mL and the median length of stay (LOS) was 1 day. Two patients (6.9%) had a perioperative complication and five (17.9%) a post-discharge complication at ≤90 days, all of which were minor. The positive surgical margin rate was 3.6% and in those with muscle-invasive disease a median of 12 lymph nodes were removed. Neither the size of diverticulum nor the need for ureteric re-implantation was predictive of LOS, EBL, or complication (P > 0.05). We did not encounter any wound, port site, or unusual recurrence patterns to suggest the technical factors of a robotic approach influenced oncological outcomes. The 5-year overall and recurrence-free survival rates were 79% and 68%, respectively.
CONCLUSION: RAPC confers the ability to achieve favourable outcomes with low morbidity and reduced hospital stays. Oncological efficacy compares favourably with the published literature. For experienced surgeons, this may represent the optimal surgical approach for organ-preserving bladder surgery.
© 2016 The Authors BJU International © 2016 BJU International Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  bladder cancer; complications; outcomes; partial cystectomy; robot-assisted

Mesh:

Year:  2016        PMID: 27207269     DOI: 10.1111/bju.13535

Source DB:  PubMed          Journal:  BJU Int        ISSN: 1464-4096            Impact factor:   5.588


  5 in total

1.  Impact of Surgical Technique on Surgical Margin Status Following Partial Cystectomy.

Authors:  Michael Owyong; Tulay Koru-Sengul; Feng Miao; Shirin Razdan; Kevin J Moore; Mahmoud Alameddine; Sanoj Punnen; Dipen J Parekh; Chad R Ritch; Mark L Gonzalgo
Journal:  Urol Oncol       Date:  2019-08-21       Impact factor: 3.498

2.  Comparison of two patients presenting with the clear cell variant of urothelial cell carcinoma of the urinary bladder: laser-assisted partial cystectomy for local disease versus chemotherapy for locally advanced disease.

Authors:  James P Blackmur; Nadja Melquiot; Katherine E Robertson; Seamus Teahan
Journal:  BMJ Case Rep       Date:  2019-06-16

3.  Perioperative outcomes of robot-assisted laparoscopic partial cystectomy.

Authors:  George C Bailey; Igor Frank; Matthew K Tollefson; Matthew T Gettman; John J Knoedler
Journal:  J Robot Surg       Date:  2017-06-10

Review 4.  Partial cystectomy for muscle-invasive bladder cancer: a review of the literature.

Authors:  Taylor C Peak; Ashok Hemal
Journal:  Transl Androl Urol       Date:  2020-12

5.  Bladder diverticulectomy using a pre-peritoneal, trans-vesicle approach with the SP platform: A novel approach.

Authors:  Michael Tonzi; Mathew J Watson; Amar Singh
Journal:  Urol Case Rep       Date:  2021-06-11
  5 in total

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