Literature DB >> 27206414

Characterization of two novel sialyl N-acetyllactosaminyl nucleotides separated from ovine colostrum.

Masashi Sasaki1, Tadashi Nakamura2, Kentaro Hirayama1, Kenji Fukuda1, Tadao Saito3, Tadasu Urashima4, Sadaki Asakuma5.   

Abstract

The milk/colostrum of some mammalian species is known to contain sugar nucleotides including uridine diphosphate (UDP) oligosaccharides in addition to lactose and milk oligosaccharides, but the detailed structures of these UDP oligosaccharides have not so far been clarified. In this study we isolated two UDP-sialyl N-acetyllactosamines from ovine colostrum and characterized them using (1)H-NMR and MALDI-TOFMS spectroscopies. Their structures were found to be Neu5Gc(α2-3)Gal(β1-4)GlcNAcα1-UDP and Neu5Gc(α2-6)Gal(β1-4)GlcNAcα1-UDP.

Entities:  

Keywords:  Milk oligosaccharide; Milk sugar nucleotide; Ovine colostrum; UDP oligosaccharide; UDP sialyl N-acetyllactosamine

Mesh：

Substances：

Year:  2016        PMID： 27206414     DOI： 10.1007/s10719-016-9672-4

Source DB:  PubMed          Journal:  Glycoconj J        ISSN： 0282-0080            Impact factor:   2.916


  29 in total

1.  Sialyllactose occurs as free lactones in ovine colostrum.

Authors:  T Nakamura; T Urashima; M Nakagawa; T Saito
Journal:  Biochim Biophys Acta       Date:  1998-08-24

2.  A comparative study of free oligosaccharides in the milk of domestic animals.

Authors:  Simone Albrecht; Jonathan A Lane; Karina Mariño; Khalid A Al Busadah; Stephen D Carrington; Rita M Hickey; Pauline M Rudd
Journal:  Br J Nutr       Date:  2014-04-14       Impact factor: 3.718

3.  Synthesis of nucleotide-activated oligosaccharides by beta-galactosidase from Bacillus circulans.

Authors:  A Zervosen; V Nieder; R G Gallego; J P Kamerling; J F Vliegenthart; L Elling
Journal:  Biol Chem       Date:  2001-02       Impact factor: 3.915

4.  The acid-soluble nucleotides of milk. IV. The chemical structure of UDP-X3.

Authors:  A Kobata
Journal:  J Biochem       Date:  1966-01       Impact factor: 3.387

5.  Chemical characterization of milk oligosaccharides of the common brushtail possum (Trichosurus vulpecula).

Authors:  Tadasu Urashima; Saori Fujita; Kenji Fukuda; Tadashi Nakamura; Tadao Saito; Phil Cowan; Michael Messer
Journal:  Glycoconj J       Date:  2014-06-07       Impact factor: 2.916

6.  Chemical characterization of acidic oligosaccharides in milk of the red kangaroo (Macropus rufus).

Authors:  Tatsuro Anraku; Kenji Fukuda; Tadao Saito; Michael Messer; Tadasu Urashima
Journal:  Glycoconj J       Date:  2012-03-14       Impact factor: 2.916

7.  Transcriptional response of HT-29 intestinal epithelial cells to human and bovine milk oligosaccharides.

Authors:  Jonathan A Lane; John O'Callaghan; Stephen D Carrington; Rita M Hickey
Journal:  Br J Nutr       Date:  2013-05-28       Impact factor: 3.718

8.  New galactosyllactose containing alpha-glycosidic linkage isolated from ovine (Booroola dorset) colostrum.

Authors:  T Urashima; T Saito; J Nishimura; H Ariga
Journal:  Biochim Biophys Acta       Date:  1989-09-15

9.  Chemical characterization of milk oligosaccharides of the common wombat (Vombatus ursinus).

Authors:  Kentaro Hirayama; Epi Taufik; Megumi Kikuchi; Tadashi Nakamura; Kenji Fukuda; Tadao Saito; Keith Newgrain; Brian Green; Michael Messer; Tadasu Urashima
Journal:  Anim Sci J       Date:  2015-11-26       Impact factor: 1.749

10.  Chemical characterization of oligosaccharides in the milk of six species of New and Old World monkeys.

Authors:  Kohta Goto; Kenji Fukuda; Akitsugu Senda; Tadao Saito; Kazumasa Kimura; Kenneth E Glander; Katie Hinde; Wolfgang Dittus; Lauren A Milligan; Michael L Power; Olav T Oftedal; Tadasu Urashima
Journal:  Glycoconj J       Date:  2010-12-03       Impact factor: 2.916
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  2 in total

1.  Chemical characterization of the milk oligosaccharides of some Artiodactyla species including giraffe (Giraffa camelopardalis), sitatunga (Tragelaphus spekii), deer (Cervus nippon yesoensis) and water buffalo (Bubalus bubalis).

Authors:  Yuri Mineguchi; Midori Miyoshi; Epi Taufik; Ayumi Kawamura; Takuya Asakawa; Isao Suzuki; Kousaku Souma; Michiko Okubo; Tadao Saito; Kenji Fukuda; Sadaki Asakuma; Tadasu Urashima
Journal:  Glycoconj J       Date:  2018-11-22       Impact factor: 2.916

2.  Characterization of Bioactive Sialyl Oligosaccharides Separated from Colostrum of Indonesia Dairy Goat.

Authors:  Epi Taufik; Irma Isnafia Arief; Cahyo Budiman; Yusuf Wibisono; Alfian Noviyanto
Journal:  Food Sci Anim Resour       Date:  2022-05-01
  2 in total

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