Literature DB >> 27206380

Mitochondrial Replacement Techniques: Divergence in Global Policy.

Johanna Schandera1, Tim K Mackey2.   

Abstract

In 2015, the UK became the first country permitting the clinical application of mitochondrial replacement techniques (MRT). Here, we explore how MRT have led to diverging international policy. In response, we recommend focused regulatory efforts coupled with United Nations (UN) leadership to build international consensus on the future of MRT.
Copyright © 2016 Elsevier Ltd. All rights reserved.

Keywords:  epigenetics; germline modification; germline regulation; mitochondrial disease.; mitochondrial donation; mitochondrial replacement techniques

Mesh:

Year:  2016        PMID: 27206380     DOI: 10.1016/j.tig.2016.04.006

Source DB:  PubMed          Journal:  Trends Genet        ISSN: 0168-9525            Impact factor:   11.639


  7 in total

Review 1.  The special considerations of gene therapy for mitochondrial diseases.

Authors:  Jesse Slone; Taosheng Huang
Journal:  NPJ Genom Med       Date:  2020-03-02       Impact factor: 8.617

2.  Beyond editing to writing large genomes.

Authors:  Raj Chari; George M Church
Journal:  Nat Rev Genet       Date:  2017-08-30       Impact factor: 53.242

3.  Mitochondrial replacement approaches: challenges for clinical implementation.

Authors:  Thomas Klopstock; Barbara Klopstock; Holger Prokisch
Journal:  Genome Med       Date:  2016-11-25       Impact factor: 11.117

Review 4.  Artificial Mitochondria Transfer: Current Challenges, Advances, and Future Applications.

Authors:  Andrés Caicedo; Pedro M Aponte; Francisco Cabrera; Carmen Hidalgo; Maroun Khoury
Journal:  Stem Cells Int       Date:  2017-07-02       Impact factor: 5.443

5.  Mitochondrial manipulation in fertility clinics: Regulation and responsibility.

Authors:  Tetsuya Ishii; Yuri Hibino
Journal:  Reprod Biomed Soc Online       Date:  2018-02-28

Review 6.  The special considerations of gene therapy for mitochondrial diseases.

Authors:  Jesse Slone; Taosheng Huang
Journal:  NPJ Genom Med       Date:  2020-03-02       Impact factor: 8.617

7.  Systematic scoping review of the concept of 'genetic identity' and its relevance for germline modification.

Authors:  Floor M Goekoop; Carla G van El; Guy A M Widdershoven; Nadza Dzinalija; Martina C Cornel; Natalie Evans
Journal:  PLoS One       Date:  2020-01-24       Impact factor: 3.240

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.