Literature DB >> 27205

The acute effects of the administration of rimiterol aerosol in asthmatic children.

M I Blackhall, B Macartney, S R O'Donnell.   

Abstract

1 Ten asthmatic children received on two separate occasions rimiterol (500 microgram) and orciprenaline (1.5 mg) as aerosols in a double-blind, crossover design trial. Respiratory parameters (FEV1, FVC and PEFR) and pulse rate were recorded for 60 min after each administration. 2 Rimiterol produced effective bronchodilation in children with negligible cardiac stimulation. It differed from orciprenaline in that the peak bronchodilator effect was not maintained during the 60 min observation period. 3 Rimiterol is a selective, short-acting, sympathomimetic bronchodilator in children.

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Year:  1978        PMID: 27205      PMCID: PMC1429394          DOI: 10.1111/j.1365-2125.1978.tb01682.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN: 0306-5251            Impact factor:   4.335


  10 in total

1.  The ventilatory capacity of normal children.

Authors:  L B STRANG
Journal:  Thorax       Date:  1959-12       Impact factor: 9.139

2.  The comparative pharmacology of WG253 (rimiterol hydrobromide), a new bronchodilator.

Authors:  I Carney; M J Daly; J E Lightowler; R W Pickering
Journal:  Arch Int Pharmacodyn Ther       Date:  1971-12

3.  The effect of a new adrenergic beta 2 -receptor-stimulating agent (rimiterol, R798) in patients with chronic obstructive lung disease.

Authors:  N Svedmyr; R Malmberg; G Thiringer
Journal:  Scand J Respir Dis       Date:  1972

4.  Potency and selectivity in vitro of compounds related to isoprenaline and orciprenaline on beta-adrenoceptors in the guinea-pig.

Authors:  S R O'Donnell; J C Wanstall
Journal:  Br J Pharmacol       Date:  1974-11       Impact factor: 8.739

5.  Clinical assessment of bronchodilator drugs delivered by aerosol.

Authors:  G M Shenfield; J W Paterson
Journal:  Thorax       Date:  1973-03       Impact factor: 9.139

6.  Comparison of the beta2-adrenoceptor selectivity of rimiterol, salbutamol and isoprenaline by the intravenous route in man.

Authors:  G E Marlin; P Turner
Journal:  Br J Clin Pharmacol       Date:  1975-02       Impact factor: 4.335

7.  Controlled comparison of the bronchodilator effects of three beta-adrenergic stimulant drugs administered by inhalation to patients with asthma.

Authors:  Y F Choo-Kang; W T Simpson; I W Grant
Journal:  Br Med J       Date:  1969-05-03

8.  Metabolism and pharmacokinetics of orciprenaline in various animal species and man.

Authors:  H G Dengler; J H Hengstmann
Journal:  Arch Int Pharmacodyn Ther       Date:  1976-09

9.  Response to rimiterol and salbutamol aerosols administered by intermittent positive-pressure ventilation.

Authors:  N J Cooke; J A Kerr; R F Willey; M V Hoare; I W Grant; G K Cromptom
Journal:  Br Med J       Date:  1974-05-04

10.  Actions of the sympathomimetic bronchodilator, rimiterol (R798), on the cardiovascular, respiratory and skeletal muscle systems of the anaesthetized cat.

Authors:  W C Bowman; I W Rodger
Journal:  Br J Pharmacol       Date:  1972-08       Impact factor: 8.739

  10 in total

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