Literature DB >> 2720428

Sensitization of cat dorsal horn neurons to innocuous mechanical stimulation after intradermal injection of capsaicin.

D A Simone1, T K Baumann, J G Collins, R H LaMotte.   

Abstract

Intradermal injection of 100 micrograms of capsaicin in cats excited dorsal horn spinal neurons classified as either 'high threshold' or 'wide dynamic range'. Capsaicin enhanced their responses to innocuous mechanical stimulation. A role for these neurons in mechanical hyperalgesia is suggested.

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Year:  1989        PMID: 2720428     DOI: 10.1016/0006-8993(89)91293-6

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  19 in total

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9.  Peripheral inflammation facilitates Abeta fiber-mediated synaptic input to the substantia gelatinosa of the adult rat spinal cord.

Authors:  H Baba; T P Doubell; C J Woolf
Journal:  J Neurosci       Date:  1999-01-15       Impact factor: 6.167

10.  Cutaneous C-fiber pain abnormalities of fibromyalgia patients are specifically related to temporal summation.

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