Literature DB >> 27203138

Medicare expenditures for elderly patients undergoing surgical clipping or endovascular intervention for subarachnoid hemorrhage.

Kimon Bekelis1,2, Daniel J Gottlieb2, Yin Su2, Giuseppe Lanzino3, Michael T Lawton4, Todd A MacKenzie5,2,6.   

Abstract

OBJECTIVE The impact of treatment method-surgical clipping or endovascular coiling-on the cost of care for patients with aneurysmal subarachnoid hemorrhage (SAH) is debated. Here, the authors investigated the association between treatment method and long-term Medicare expenditures in elderly patients with aneurysmal SAH. METHODS The authors performed a cohort study of 100% of the Medicare fee-for-service claims data for elderly patients who had undergone treatment for ruptured cerebral aneurysms in the period from 2007 to 2012. To control for measured confounding, the authors used propensity score-adjusted multivariable regression analysis with mixed effects to account for clustering at the hospital referral region (HRR) level. An instrumental variable (regional rates of coiling) analysis was used to control for unmeasured confounding by creating pseudo-randomization on the treatment method. RESULTS During the study period, 3210 patients underwent treatment for ruptured cerebral aneurysms and met the inclusion criteria. Of these patients, 1206 (37.6%) had surgical clipping and 2004 (62.4%) had endovascular coiling. The median total Medicare expenditures in the 1st year after admission for SAH were $113,000 (IQR $77,500-$182,000) for surgical clipping and $103,000 (IQR $72,900-$159,000) for endovascular coiling. When the authors adjusted for unmeasured confounders by using an instrumental variable analysis, clipping was associated with increased 1-year Medicare expenditures by $19,577 (95% CI $4492-$34,663). CONCLUSIONS In a cohort of Medicare patients with aneurysmal SAH, after controlling for unmeasured confounding, surgical clipping was associated with increased 1-year expenditures in comparison with endovascular coiling.

Entities:  

Keywords:  COPD = chronic obstructive pulmonary disease; HRR = hospital referral region; ISAT = International Subarachnoid Aneurysm Trial; IV = instrumental variable; Medicare; NIS = Nationwide Inpatient Sample; SAH = subarachnoid hemorrhage; ZIP = Zone Improvement Program; cerebral aneurysms; clipping; coiling; cost; instrumental variable; subarachnoid hemorrhage; vascular disorders

Mesh:

Year:  2016        PMID: 27203138      PMCID: PMC5549790          DOI: 10.3171/2016.2.JNS152994

Source DB:  PubMed          Journal:  J Neurosurg        ISSN: 0022-3085            Impact factor:   5.115


  36 in total

1.  Impact of case volume on aneurysmal subarachnoid hemorrhage outcomes.

Authors:  Tiffany R Chang; Robert G Kowalski; J Ricardo Carhuapoma; Rafael J Tamargo; Neeraj S Naval
Journal:  J Crit Care       Date:  2015-01-10       Impact factor: 3.425

2.  Uncertainty and agreement in the management of unruptured intracranial aneurysms.

Authors:  Tim E Darsaut; Laurent Estrade; Sara Jamali; Michel W Bojanowski; Miguel Chagnon; Jean Raymond
Journal:  J Neurosurg       Date:  2014-01-03       Impact factor: 5.115

3.  Impact of International Subarachnoid Aneurysm Trial results on treatment of ruptured intracranial aneurysms in the United States. Clinical article.

Authors:  Adnan I Qureshi; Gabriela Vazquez; Nauman Tariq; M Fareed K Suri; Kamakshi Lakshminarayan; Giuseppe Lanzino
Journal:  J Neurosurg       Date:  2010-07-23       Impact factor: 5.115

4.  A predictive model of outcomes during cerebral aneurysm coiling.

Authors:  Kimon Bekelis; Symeon Missios; Todd A Mackenzie; Adina Fischer; Nicos Labropoulos; Clifford Eskey
Journal:  J Neurointerv Surg       Date:  2013-07-04       Impact factor: 5.836

Review 5.  Safety and occlusion rates of surgical treatment of unruptured intracranial aneurysms: a systematic review and meta-analysis of the literature from 1990 to 2011.

Authors:  Marc Kotowski; Olivier Naggara; Tim E Darsaut; Suzanne Nolet; Guylaine Gevry; Evgueni Kouznetsov; Jean Raymond
Journal:  J Neurol Neurosurg Psychiatry       Date:  2012-09-25       Impact factor: 10.154

6.  Comparative effectiveness of unruptured cerebral aneurysm therapies: propensity score analysis of clipping versus coiling.

Authors:  Jennifer S McDonald; Robert J McDonald; Jiaquan Fan; David F Kallmes; Giuseppe Lanzino; Harry J Cloft
Journal:  Stroke       Date:  2013-02-28       Impact factor: 7.914

7.  Age-related trends in the treatment and outcomes of ruptured cerebral aneurysms: a study of the nationwide inpatient sample 2001-2009.

Authors:  W Brinjikji; G Lanzino; A A Rabinstein; D F Kallmes; H J Cloft
Journal:  AJNR Am J Neuroradiol       Date:  2012-11-01       Impact factor: 3.825

8.  Treatment pathways, resource use, and costs of endovascular coiling versus surgical clipping after aSAH.

Authors:  Jane Wolstenholme; Oliver Rivero-Arias; Alastair Gray; Andrew J Molyneux; Richard S C Kerr; Julia A Yarnold; Mary Sneade
Journal:  Stroke       Date:  2007-11-29       Impact factor: 7.914

9.  Comparative Cost Analysis for Surgical and Endovascular Treatment of Unruptured Intracranial Aneurysms in South Korea.

Authors:  Myungsoo Kim; Jaechan Park; Joomi Lee
Journal:  J Korean Neurosurg Soc       Date:  2015-06-30

10.  New York State: Comparison of Treatment Outcomes for Unruptured Cerebral Aneurysms Using an Instrumental Variable Analysis.

Authors:  Kimon Bekelis; Symeon Missios; Shannon Coy; Robert J Singer; Todd A MacKenzie
Journal:  J Am Heart Assoc       Date:  2015-07-13       Impact factor: 5.501

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  3 in total

1.  Racial and Ethnic Disparities in Treatment Outcomes of Patients with Ruptured or Unruptured Intracranial Aneurysms.

Authors:  Hind A Beydoun; May A Beydoun; Alan B Zonderman; Shaker M Eid
Journal:  J Racial Ethn Health Disparities       Date:  2018-09-27

2.  Effect of patient age on glioblastoma perioperative treatment costs: a value driven outcome database analysis.

Authors:  Brandon A Sherrod; Nicholas T Gamboa; Christopher Wilkerson; Herschel Wilde; Mohammed A Azab; Michael Karsy; Randy L Jensen; Sarah T Menacho
Journal:  J Neurooncol       Date:  2019-05-04       Impact factor: 4.130

3.  Perioperative Ischemic Stroke in Unruptured Intracranial Aneurysm Surgical or Endovascular Therapy.

Authors:  Hind A Beydoun; May Beydoun; Alan Zonderman; Shaker M Eid
Journal:  Cureus       Date:  2020-04-12
  3 in total

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