S Cope1, A Clemens2, F Hammès3, H Noack4, J Jansen5. 1. Mapi, Inc., Toronto, ON, Canada. 2. Boehringer Ingelheim Pharma GmbH & Co KG, Corporate Devision Medicine, Ingelheim, Germany. 3. Boehringer Ingelheim, Paris, France. 4. Boehringer Ingelheim Pharma GmbH & Co KG, Medical Data Services, Ingelheim, Germany. 5. Tufts University School of Medicine, Boston, MA, USA.