Literature DB >> 2719978

Monooxygenation of N-acetylhistamine mediated by L-ascorbate.

K Uchida1, M Mitsui, S Kawakishi.   

Abstract

In the presence of molecular oxygen and a catalytic amount of copper(II) ion, ascorbate almost completely degraded histamine (approx. 72%). The reaction was shown to occur at the imidazole group but not at the primary amino group in histamine. 4-[2-(Acetylamino)ethyl]-2,3-dihydroimidazol-2-one, a monooxygenated form of N-acetylhistamine, was first isolated as the primary product.

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Year:  1989        PMID： 2719978     DOI： 10.1016/0304-4165(89)90131-1

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  8 in total

1.  Intravenous infusion of ascorbic acid decreases serum histamine concentrations in patients with allergic and non-allergic diseases.

Authors:  Alexander F Hagel; Christian M Layritz; Wolfgang H Hagel; Hans-Jürgen Hagel; Edith Hagel; Wolfgang Dauth; Jürgen Kressel; Tanja Regnet; Andreas Rosenberg; Markus F Neurath; Gerhard J Molderings; Martin Raithel
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2013-05-11       Impact factor: 3.000

2.  Effect of antioxidants on histamine receptor activation and sustained postexercise vasodilatation in humans.

Authors:  Steven A Romero; Matthew R Ely; Dylan C Sieck; Meredith J Luttrell; Tahisha M Buck; Jordan M Kono; Adam J Branscum; John R Halliwill
Journal:  Exp Physiol       Date:  2015-03-25       Impact factor: 2.969

3.  Inter-relationship of plasma markers of oxidative stress and thyroid hormones in schizophrenics.

Authors:  Moses O Akiibinu; Omobola A Ogundahunsi; Ebenezer O Ogunyemi
Journal:  BMC Res Notes       Date:  2012-03-31

Review 4.  Zinc, Vitamin D and Vitamin C: Perspectives for COVID-19 With a Focus on Physical Tissue Barrier Integrity.

Authors:  José João Name; Ana Carolina Remondi Souza; Andrea Rodrigues Vasconcelos; Pietra Sacramento Prado; Carolina Parga Martins Pereira
Journal:  Front Nutr       Date:  2020-12-07

5.  Histamine as a marker for hydroxyl radicals.

Authors:  T L Ching; R M Hee; N M Bhoelan; J Blauw; W M Menge; J de Jong; A Bast
Journal:  Mediators Inflamm       Date:  1995       Impact factor: 4.711

6.  Vitamin C supplementation slightly improves physical activity levels and reduces cold incidence in men with marginal vitamin C status: a randomized controlled trial.

Authors:  Carol S Johnston; Gillean M Barkyoumb; Sara S Schumacher
Journal:  Nutrients       Date:  2014-07-09       Impact factor: 5.717

7.  Effects of Dietary Supplementation with Astaxanthin on Histamine Induced Lesions in the Gizzard and Proventriculus of Broiler Chicks.

Authors:  Mi-Hyang Ohh; Seongjin Kim; Sok Cheon Pak; Kew-Mahn Chee
Journal:  Asian-Australas J Anim Sci       Date:  2016-01-29       Impact factor: 2.509

Review 8.  Pharmacological treatment options for mast cell activation disease.

Authors:  Gerhard J Molderings; Britta Haenisch; Stefan Brettner; Jürgen Homann; Markus Menzen; Franz Ludwig Dumoulin; Jens Panse; Joseph Butterfield; Lawrence B Afrin
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2016-04-30       Impact factor: 3.000
  8 in total

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