| Literature DB >> 27199460 |
Flonza Isa1, Kohta Saito1, Yao-Ting Huang2, Audrey Schuetz3, N Esther Babady4, Steven Salvatore3, Melissa Pessin4, Koen van Besien5, Miguel-Angel Perales6, Sergio Giralt6, Kent Sepkowitz7, Genovefa A Papanicolaou8, Rosemary Soave1, Mini Kamboj7.
Abstract
After a cluster of fatal toxoplasmosis among stem cell transplant recipients at 2 hospitals, surveillance with polymerase chain reaction (PCR) (blood) was instituted. Rate of reactivation among seropositive recipients was 2.2 and 16%. Parasitemia was successfully managed with preemptive treatment. For seropositive recipients unable to take prophylaxis, toxoplasma PCR surveillance should be routinely performed.Entities:
Keywords: CD34+ selected; T-cell depleted; reactivation; stem cell transplant; toxoplasmosis
Mesh:
Year: 2016 PMID: 27199460 PMCID: PMC4967604 DOI: 10.1093/cid/ciw330
Source DB: PubMed Journal: Clin Infect Dis ISSN: 1058-4838 Impact factor: 9.079