Elie Guichard1, Ilaria Montagni2,3, Christophe Tzourio2,3, Tobias Kurth4. 1. INSERM CIC1415, CHRU de Tours, Tours, France. 2. University of Bordeaux, UMR1219, Bordeaux, France. 3. INSERM, HEALTHY Team, UMR1219, Bordeaux, France. 4. Institute of Public Health, Charité - Universitätsmedizin Berlin, Germany.
Abstract
OBJECTIVE: To study the association between migraine and tinnitus in a large, cross-sectional study among students. BACKGROUND: Tinnitus has been associated with various pain syndromes, including headaches. However, prior studies were mainly conducted among elderly adults. METHODS: Cross-sectional study among 5729 participants of the French internet-based Students Health Research Enterprise (i-Share) cohort. Health, personal and lifestyle habits, and socio-demographics characteristics as well as headache/migraine symptoms and tinnitus, were recorded in a standardized questionnaire based on self-reports. Logistic regression models were used to evaluate the association between the students' headache status and tinnitus. RESULTS: The 5729 participants had a mean age of 20.8 years (standard deviation 2.8 years), 75.4% were female, and 1645 reported migraine. An association was found between the students' headache status and tinnitus after adjustment for confounding variables. Tinnitus was reported by 8.9% of participants with migraine, 7.3% of patients with migraine without aura, and 10.8% of participants with migraine with aura. The adjusted odds ratios of tinnitus were 1.77 (95% confidence interval, 1.36-2.30) for migraine and 1.38 (0.98-1.92) for non-migraine headache. The association was stronger for students with migraine with aura (odds ratio = 2.10, 95% confidence interval 1.54-2.86) than for migraine without aura (odds ratio = 1.51, 95% confidence interval 1.09-2.07). CONCLUSION: We found an association between migraine and tinnitus among young individuals, which was strongest for the subgroup migraine with aura.
OBJECTIVE: To study the association between migraine and tinnitus in a large, cross-sectional study among students. BACKGROUND:Tinnitus has been associated with various pain syndromes, including headaches. However, prior studies were mainly conducted among elderly adults. METHODS: Cross-sectional study among 5729 participants of the French internet-based Students Health Research Enterprise (i-Share) cohort. Health, personal and lifestyle habits, and socio-demographics characteristics as well as headache/migraine symptoms and tinnitus, were recorded in a standardized questionnaire based on self-reports. Logistic regression models were used to evaluate the association between the students' headache status and tinnitus. RESULTS: The 5729 participants had a mean age of 20.8 years (standard deviation 2.8 years), 75.4% were female, and 1645 reported migraine. An association was found between the students' headache status and tinnitus after adjustment for confounding variables. Tinnitus was reported by 8.9% of participants with migraine, 7.3% of patients with migraine without aura, and 10.8% of participants with migraine with aura. The adjusted odds ratios of tinnitus were 1.77 (95% confidence interval, 1.36-2.30) for migraine and 1.38 (0.98-1.92) for non-migraineheadache. The association was stronger for students with migraine with aura (odds ratio = 2.10, 95% confidence interval 1.54-2.86) than for migraine without aura (odds ratio = 1.51, 95% confidence interval 1.09-2.07). CONCLUSION: We found an association between migraine and tinnitus among young individuals, which was strongest for the subgroup migraine with aura.
Authors: Benjamin Boecking; Josephine von Sass; Antonia Sieveking; Christina Schaefer; Petra Brueggemann; Matthias Rose; Birgit Mazurek Journal: PLoS One Date: 2020-06-25 Impact factor: 3.240