Literature DB >> 27197568

Metabolic control of asyMYCtric division.

Mytrang H Do1,2, Ming O Li1.   

Abstract

Asymmetric division in CD8 T cells produces two daughter cells expressing different levels of c-Myc with distinct metabolic profiles. Manipulating this asymmetric partitioning of c-Myc skews T cell responses and potentially allows the development of more effective vaccines and cancer immunotherapies.

Entities:  

Mesh：

Year:  2016        PMID： 27197568      PMCID： PMC4973327          DOI： 10.1038/cr.2016.60

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


  9 in total

Review 1.  Asymmetric cell division during animal development.

Authors:  J A Knoblich
Journal:  Nat Rev Mol Cell Biol       Date:  2001-01       Impact factor: 94.444

2.  Asymmetric T lymphocyte division in the initiation of adaptive immune responses.

Authors:  John T Chang; Vikram R Palanivel; Ichiko Kinjyo; Felix Schambach; Andrew M Intlekofer; Arnob Banerjee; Sarah A Longworth; Kristine E Vinup; Paul Mrass; Jane Oliaro; Nigel Killeen; Jordan S Orange; Sarah M Russell; Wolfgang Weninger; Steven L Reiner
Journal:  Science       Date:  2007-03-01       Impact factor: 47.728

3.  Asymmetric proteasome segregation as a mechanism for unequal partitioning of the transcription factor T-bet during T lymphocyte division.

Authors:  John T Chang; Maria L Ciocca; Ichiko Kinjyo; Vikram R Palanivel; Courtney E McClurkin; Caitlin S Dejong; Erin C Mooney; Jiyeon S Kim; Natalie C Steinel; Jane Oliaro; Catherine C Yin; Bogdan I Florea; Herman S Overkleeft; Leslie J Berg; Sarah M Russell; Gary A Koretzky; Martha S Jordan; Steven L Reiner
Journal:  Immunity       Date:  2011-04-14       Impact factor: 31.745

4.  Tsc1 promotes the differentiation of memory CD8+ T cells via orchestrating the transcriptional and metabolic programs.

Authors:  Sharad Shrestha; Kai Yang; Jun Wei; Peer W F Karmaus; Geoffrey Neale; Hongbo Chi
Journal:  Proc Natl Acad Sci U S A       Date:  2014-09-30       Impact factor: 11.205

5.  Asymmetric PI3K Signaling Driving Developmental and Regenerative Cell Fate Bifurcation.

Authors:  Wen-Hsuan W Lin; William C Adams; Simone A Nish; Yen-Hua Chen; Bonnie Yen; Nyanza J Rothman; Radomir Kratchmarov; Takaharu Okada; Ulf Klein; Steven L Reiner
Journal:  Cell Rep       Date:  2015-11-25       Impact factor: 9.423

6.  The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation.

Authors:  Ruoning Wang; Christopher P Dillon; Lewis Zhichang Shi; Sandra Milasta; Robert Carter; David Finkelstein; Laura L McCormick; Patrick Fitzgerald; Hongbo Chi; Joshua Munger; Douglas R Green
Journal:  Immunity       Date:  2011-12-23       Impact factor: 31.745

7.  T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming.

Authors:  Kai Yang; Sharad Shrestha; Hu Zeng; Peer W F Karmaus; Geoffrey Neale; Peter Vogel; David A Guertin; Richard F Lamb; Hongbo Chi
Journal:  Immunity       Date:  2013-12-05       Impact factor: 31.745

8.  Asymmetric inheritance of mTORC1 kinase activity during division dictates CD8(+) T cell differentiation.

Authors:  Kristen N Pollizzi; Im-Hong Sun; Chirag H Patel; Ying-Chun Lo; Min-Hee Oh; Adam T Waickman; Ada J Tam; Richard L Blosser; Jiayu Wen; Greg M Delgoffe; Jonathan D Powell
Journal:  Nat Immunol       Date:  2016-04-11       Impact factor: 25.606

9.  Metabolic maintenance of cell asymmetry following division in activated T lymphocytes.

Authors:  Katherine C Verbist; Cliff S Guy; Sandra Milasta; Swantje Liedmann; Marcin M Kamiński; Ruoning Wang; Douglas R Green
Journal:  Nature       Date:  2016-04-11       Impact factor: 49.962
  9 in total

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