OBJECTIVE: To investigate the application value of parathyroid hormone (PTH) within 24 hours in predicting post-operative hypocalcemia after total thyroidectomy. METHOD: In this study, we selected 207 consecutive patients, performed total thyroidectomy in our hospital, measured the serum PTH and electrolyte, divided them into subgroups according to the definition of post-operative hypocalcemia, and made the ROC curves analysis combining with clinical data. RESULT: The mean value of pre-operative PTHs between groups. show no significant difference (P > 0.05); in the first day after surgery, the post-operative hypocalcemia group have a significant lower average PTHs (P < 0.01). ROC area under the curve (AUC) of day-1 is 0.886, with the PTH cutoff value 16. 8 pg/ml. CONCLUSION: The PTH within 24 hours is an important indicator to judging post-operative hypocalcermia after total thyroidectomy.
OBJECTIVE: To investigate the application value of parathyroid hormone (PTH) within 24 hours in predicting post-operative hypocalcemia after total thyroidectomy. METHOD: In this study, we selected 207 consecutive patients, performed total thyroidectomy in our hospital, measured the serum PTH and electrolyte, divided them into subgroups according to the definition of post-operative hypocalcemia, and made the ROC curves analysis combining with clinical data. RESULT: The mean value of pre-operative PTHs between groups. show no significant difference (P > 0.05); in the first day after surgery, the post-operative hypocalcemia group have a significant lower average PTHs (P < 0.01). ROC area under the curve (AUC) of day-1 is 0.886, with the PTH cutoff value 16. 8 pg/ml. CONCLUSION: The PTH within 24 hours is an important indicator to judging post-operative hypocalcermia after total thyroidectomy.
Authors: Kathrin Nagel; Anne Hendricks; Christina Lenschow; Michael Meir; Stefanie Hahner; Martin Fassnacht; Armin Wiegering; Christoph-Thomas Germer; Nicolas Schlegel Journal: BJS Open Date: 2022-09-02
Authors: Alberto Maria Saibene; Cecilia Rosso; Mario Gennaro Cozzolino; Loredana De Pasquale; Giovanni Felisati; Carlotta Pipolo; Simone De Leo; Paolo Lozza Journal: Updates Surg Date: 2021-09-26