Literature DB >> 27193724

The level of the Phf10 protein, a PBAF chromatin-remodeling complex subunit, correlates with the Mts1/S100A4 expression in human cancer cell lines.

N V Soshnikova1, Yu P Simonov2, A V Brechalov2, T N Portseva2, E V Pankratova2, S G Georgieva2.   

Abstract

Mts1 (S100A4) protein is a marker of metastatic tumor cells, which is associated with a poor diagnostic prognosis for cancer progression. Therefore, it is important to study the S100A4 gene expression. According to our preliminary data, PHF10, a PBAF remodeling complex component, can play an important role in the transcription regulation of the S100A4 gene. We studied the expression of S100A4 and the total PHF10 protein in some cell lines. We have found that, in the cell lines studied, the PHF10 expression is correlated with the S100A4 expression.

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Year:  2016        PMID： 27193724     DOI： 10.1134/S1607672916020228

Source DB:  PubMed          Journal:  Dokl Biochem Biophys        ISSN： 1607-6729            Impact factor:   0.788


  11 in total

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9.  Mammalian cells contain two functionally distinct PBAF complexes incorporating different isoforms of PHF10 signature subunit.

Authors:  Alexander V Brechalov; Sofia G Georgieva; Nataliya V Soshnikova
Journal:  Cell Cycle       Date:  2014-04-24       Impact factor: 4.534

10.  Oct-2 forms a complex with Oct-1 on the iNOS promoter and represses transcription by interfering with recruitment of RNA PolII by Oct-1.

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Journal:  Nucleic Acids Res       Date:  2015-08-13       Impact factor: 16.971
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  1 in total

Review 1.  Conserved Structure and Evolution of DPF Domain of PHF10-The Specific Subunit of PBAF Chromatin Remodeling Complex.

Authors:  Anton O Chugunov; Nadezhda A Potapova; Natalia S Klimenko; Victor V Tatarskiy; Sofia G Georgieva; Nataliya V Soshnikova
Journal:  Int J Mol Sci       Date:  2021-10-15       Impact factor: 5.923
  1 in total

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