Literature DB >> 27193720

Transcriptional control of insulin-sensitive glucose carrier Glut4 expression in adipose tissue cells.

D N Penkov1, Zh A Akopyan2, T N Kochegura2, A D Egorov2.   

Abstract

In search for new targets for obesity treatment, we have studied the effect of several transcription factors on the conversion of murine preadipocytes from the 3T3-L1 cell line into adipocytes. We have found that knockdown of Prep1 gene expression affects adipogenic differentiation and results in significant increase in the insulin-sensitive glucose carrier Glut4 gene expression.

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Year:  2016        PMID： 27193720     DOI： 10.1134/S1607672916020186

Source DB:  PubMed          Journal:  Dokl Biochem Biophys        ISSN： 1607-6729            Impact factor:   0.788


  10 in total

Review 1.  The GLUT4 glucose transporter.

Authors:  Shaohui Huang; Michael P Czech
Journal:  Cell Metab       Date:  2007-04       Impact factor: 27.287

2.  Prep1 deficiency induces protection from diabetes and increased insulin sensitivity through a p160-mediated mechanism.

Authors:  Francesco Oriente; Luis Cesar Fernandez Diaz; Claudia Miele; Salvatore Iovino; Silvia Mori; Victor Manuel Diaz; Giancarlo Troncone; Angela Cassese; Pietro Formisano; Francesco Blasi; Francesco Beguinot
Journal:  Mol Cell Biol       Date:  2008-07-21       Impact factor: 4.272

3.  Transcriptional regulation of the insulin-responsive glucose transporter GLUT4 gene: from physiology to pathology.

Authors:  Eddy Karnieli; Michal Armoni
Journal:  Am J Physiol Endocrinol Metab       Date:  2008-05-20       Impact factor: 4.310

4.  Transcription factor cooperativity in early adipogenic hotspots and super-enhancers.

Authors:  Rasmus Siersbæk; Atefeh Rabiee; Ronni Nielsen; Simone Sidoli; Sofie Traynor; Anne Loft; Lars La Cour Poulsen; Adelina Rogowska-Wrzesinska; Ole N Jensen; Susanne Mandrup
Journal:  Cell Rep       Date:  2014-05-22       Impact factor: 9.423

5.  PBX1: a novel stage-specific regulator of adipocyte development.

Authors:  Miguel C Monteiro; Mrinmoy Sanyal; Michael L Cleary; Coralie Sengenès; Anne Bouloumié; Anne Bouloumé; Christian Dani; Nathalie Billon
Journal:  Stem Cells       Date:  2011-11       Impact factor: 6.277

6.  Insulin and sterol-regulatory element-binding protein-1c (SREBP-1C) regulation of gene expression in 3T3-L1 adipocytes. Identification of CCAAT/enhancer-binding protein beta as an SREBP-1C target.

Authors:  Soazig Le Lay; Isabelle Lefrère; Christian Trautwein; Isabelle Dugail; Stéphane Krief
Journal:  J Biol Chem       Date:  2002-06-04       Impact factor: 5.157

7.  A third-generation lentivirus vector with a conditional packaging system.

Authors:  T Dull; R Zufferey; M Kelly; R J Mandel; M Nguyen; D Trono; L Naldini
Journal:  J Virol       Date:  1998-11       Impact factor: 5.103

8.  Early B-cell factor (O/E-1) is a promoter of adipogenesis and involved in control of genes important for terminal adipocyte differentiation.

Authors:  Peter Akerblad; Ulrika Lind; David Liberg; Krister Bamberg; Mikael Sigvardsson
Journal:  Mol Cell Biol       Date:  2002-11       Impact factor: 4.272

9.  Prep1 controls insulin glucoregulatory function in liver by transcriptional targeting of SHP1 tyrosine phosphatase.

Authors:  Francesco Oriente; Salvatore Iovino; Serena Cabaro; Angela Cassese; Elena Longobardi; Claudia Miele; Paola Ungaro; Pietro Formisano; Francesco Blasi; Francesco Beguinot
Journal:  Diabetes       Date:  2010-09-23       Impact factor: 9.461

10.  Overexpression of PREP-1 in F9 teratocarcinoma cells leads to a functionally relevant increase of PBX-2 by preventing its degradation.

Authors:  Elena Longobardi; Francesco Blasi
Journal:  J Biol Chem       Date:  2003-07-18       Impact factor: 5.157
  10 in total

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