| Literature DB >> 27191582 |
Thanasan Nilsu1, Sakornrat Thorroad2, Somsak Ruchirawat2, Nopporn Thasana2.
Abstract
Two new Lycopodium alkaloids, squarrosine A (1) and pyrrolhuperzine A (2), were isolated from the Thai and Philippine plant Huperzia squarrosa. (R)-2-Piperidineacetic acid (5) was a known alkaloid, but has now been isolated for the first time from a natural source. Their structures were elucidated using extensive spectroscopic analyses and, for pyrrolhuperzine A (2), confirmation by chemical transformation. The new compounds exhibited moderate acetylcholinesterase inhibitory activities. Georg Thieme Verlag KG Stuttgart · New York.Entities:
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Year: 2016 PMID： 27191582 DOI： 10.1055/s-0042-106904
Source DB: PubMed Journal: Planta Med ISSN： 0032-0943 Impact factor: 3.352