Literature DB >> 27190950

A Comparison of the Effectiveness of Oral Midazolam -N2O Versus Oral Ketamine - N2O in Pediatric Patients-An in-Vivo Study.

Vasanthi Done1, Ravichandrasekhar Kotha2, Aron Arun Kumar Vasa1, Suzan Sahana1, Raghavendra Kumar Jadadoddi3, Sushma Bezawada3.   

Abstract

INTRODUCTION: Most children are casual and moderately agreeable in the dental treatment environment, however some of them show practices that upset the professional and make the protected conveyance of worthy treatment extremely troublesome. For such cases dental practitioner utilizes behavior management techniques. At the point when behavioral administration procedures come up short, some type of pharmacologic sedation or anesthesia may be an important and vital option. Dental sedation is a strategy in which the utilization of a medication or drugs produce(s) a condition of depression of the central sensory system empowering treatment to be completed during which verbal contact with the patient is kept up all through the time of sedation. AIM: This study was designed to evaluate and compare the effectiveness of oral midazolam and oral ketamine in combination with N2O-O2 in children undergoing dental treatment.
MATERIALS AND METHODS: This study involved a sample of 30 pediatric dental patients (age range is 3-9 years), whose selection criteria included ASA I & II health status, cooperative but apprehensive behavior and a need for multiple dental extractions. The patients were assigned to receive oral midazolam on their first visit and on the follow up visit they received oral ketamine. Nitrous oxide (30%) was used during each sedation visit. Physiological parameters like Respiratory Rate (RR), pulse rate, and oxygen saturation were evaluated for each procedure, followed by the use of modified Bender Visual Motor Gestalt Test to evaluate psychomotor effects. Data were analyzed using Independent sample student t -test.
RESULTS: Analysis of the data showed statistically no significant difference (p >0.05) on comparison of effectiveness of oral midazolam-N2O with oral ketamine-N2O when pulse rate, oxygen saturation and respiratory rate were taken into consideration. Psychomotor performance was found to be marginally better with oral midazolam-N2O compared to oral ketamine-N2O.
CONCLUSION: Both the drugs were effective in reducing the patient anxiety while undergoing dental extractions. Though the t-test results were not statistically significant with respect to physiological parameters. Oral midazolam-N2O showed marginally better results compared to oral ketamine-N2O with respect to psychomotor effects.

Entities:  

Keywords:  Anxious pediatric patients; Conscious sedation; Dental procedures; Premedication

Year:  2016        PMID: 27190950      PMCID: PMC4866248          DOI: 10.7860/JCDR/2016/16760.7592

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  17 in total

1.  Clinical effects of nitrous oxide conscious sedation in children.

Authors:  Milton I Houpt; Robert Limb; Richard L Livingston
Journal:  Pediatr Dent       Date:  2004 Jan-Feb       Impact factor: 1.874

2.  Nasal versus oral midazolam sedation for pediatric dental patients.

Authors:  Su Jun Lee-Kim; Shahrbanoo Fadavi; Indru Punwani; Anne Koerber
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Review 4.  Safety of oral midazolam sedation use in paediatric dentistry: a review.

Authors:  Arathi Papineni; Liege Lourenço-Matharu; Paul F Ashley
Journal:  Int J Paediatr Dent       Date:  2012-12-13       Impact factor: 3.455

5.  Comparison of chloral hydrate with and without promethazine in the sedation of young children.

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Journal:  Pediatr Dent       Date:  1985-03       Impact factor: 1.874

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Authors:  K E Wilson; R R Welbury; N M Girdler
Journal:  Br Dent J       Date:  2002-04-27       Impact factor: 1.626

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Authors:  C Sekerci; A Dönmez; Y Ateş; F Okten
Journal:  Eur J Anaesthesiol       Date:  1996-11       Impact factor: 4.330

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Authors:  B M Smith; B J Cutilli; W Saunders
Journal:  Compend Contin Educ Dent       Date:  1998-06

10.  Comparison of oral midazolam with a combination of oral midazolam and nitrous oxide-oxygen inhalation in the effectiveness of dental sedation for young children.

Authors:  A M Al-Zahrani; Amjad H Wyne; S A Sheta
Journal:  J Indian Soc Pedod Prev Dent       Date:  2009 Jan-Mar
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  1 in total

Review 1.  Trends for in-office usage of pharmacological sedation agents in India: A narrative review.

Authors:  Sakshi Joshi; Anil Gupta; Shalini Garg; Shikha Dogra
Journal:  J Anaesthesiol Clin Pharmacol       Date:  2021-11-02
  1 in total

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